重症监护室呼吸机相关性肺炎病原菌分布与耐药性研究

发布时间：2017-12-28 23:01

本文关键词：重症监护室呼吸机相关性肺炎病原菌分布与耐药性研究　出处：《中国消毒学杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的研究医院重症监护室(ICU)呼吸机相关性肺炎(VAP)病原菌的分布及其耐药性,为制定有效控制VAP的措施提供依据。方法通过回顾性分析方法,对某医院ICU住院VAP患者病原学标本检验结果进行统计分析。结果该医院ICU连续3年从VAP患者送检标本中共分离出病原菌367株,其中革兰阴性菌占69.75%;革兰阳性球菌和真菌分别占22.07%和8.18%。分离菌株居前5位依次是鲍曼不动杆菌、肺炎克雷伯菌、铜绿假单胞菌、金黄色葡萄球菌和大肠埃希菌。VAP患者标本分离的鲍曼不动杆菌和铜绿假单胞菌对多数抗菌药物的耐药率均超过50%。结论该ICU患者VAP病原菌以革兰阴性菌为主,其耐药率较高,应合理使用抗菌药物,降低病原菌的耐药率。
[Abstract]:Objective to study the distribution and drug resistance of the pathogenic bacteria of ventilator associated pneumonia (VAP) in ICU, and to provide a basis for the formulation of effective measures to control VAP. Methods through retrospective analysis, the test results of the pathogenic samples of VAP patients in a hospital ICU were statistically analyzed. Results a total of 367 isolates of pathogens were isolated from ICU patients in 3 consecutive years from the hospital in, of which gram negative bacteria accounted for 69.75%, gram-positive cocci and fungi accounted for 22.07% and 8.18%, respectively. The top 5 isolates were Acinetobacter, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli in the first 5. The resistance rates of Acinetobacter sp. Bauman and Pseudomonas aeruginosa to most of the VAP patients were more than 50%. Conclusion the VAP pathogenic bacteria in the ICU patients are mainly Gram-negative bacteria, and their resistance rate is high. The antibiotics should be used reasonably to reduce the resistance rate of the pathogenic bacteria.
【作者单位】：杭州市西湖区第二人民医院;
【分类号】：R563.1;R446.5
【正文快照】： 呼吸机相关性肺炎(VAP)是指无肺部感染的患者,在予以气管插管或气管切开实施机械通气48 h后出现的肺部感染,或在原有肺部感染的基础上,在机械通气后发生新的肺部感染。VAP是机械通气治疗中常见而严重的并发症,发病率和病死率均比较高〔1〕。为了解和掌握医院住院患者VAP病原菌

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