乙肝肝硬化背景小肝癌CT与MRI强化特征的比较研究

发布时间：2017-12-31 16:41

本文关键词：乙肝肝硬化背景小肝癌CT与MRI强化特征的比较研究　出处：《临床放射学杂志》2016年01期 　论文类型：期刊论文

【摘要】：目的比较乙肝肝硬化背景小肝癌(SHCC)CT与MRI的强化特征。方法 87例乙肝肝硬化SHCC患者共计91个病灶均行CT和MRI动态增强扫描,分别测量病灶平扫及增强各期CT值和MRI信号强度值,计算增强后CT与MRI各期相对强化率和病灶-肝脏对比率,绘制时间-密度/信号强度曲线并分型,观察记录病灶CT与MRI动脉期强化方式及假包膜的显示情况,分析比较乙肝肝硬化背景SHCC CT与MRI的强化特征。结果 MRI动脉期及平衡期SHCC相对强化率较CT高,差异有统计学意义(P0.05),CT与MRI门静脉期SHCC相对强化率差异无统计学意义(P0.05)。MRI动脉期、门静脉期及平衡期SHCC病灶-肝脏对比率均较CT高,差异均有统计学意义(P0.05)。CT与MRI SHCC时间-密度/信号强度曲线类型差异有统计学意义(P0.05),两两比较速升速降型及速升缓降型差异有统计学意义(P0.05),缓慢上升型及基本无强化型差异无统计学意义(P0.05)。CT与MRI SHCC动脉期强化方式差异无统计学意义(P0.05)。MRI动态增强SHCC假包膜显示率较CT高,差异有统计学意义(P0.05)。结论 CT和MRI动态增强都能很好地反映SHCC相对肝实质的"快进快出"的强化方式,MRI对显示SHCC动脉期快速强化的特征及假包膜较CT有优势,而CT更有利于观察SHCC强化"退出"的特点。
[Abstract]:Objective to compare the background of liver cirrhosis with small hepatocellular carcinoma (SHCC). Methods Ninety-one lesions in 87 patients with hepatitis B cirrhosis with SHCC were examined by dynamic enhanced CT and MRI. The CT value and MRI signal intensity of each phase were measured respectively. The relative enhancement rate of CT and MRI and the ratio of focus to liver were calculated. The time-density / signal intensity curves were drawn and classified to record the enhancement mode of CT and MRI arterial phase and the display of pseudocapsule. Results the relative enhancement rate of SHCC in arterial phase and equilibrium phase of MRI was higher than that of CT. There was no significant difference in the relative enhancement rate of SHCC between CT and MRI in portal phase. The focus-liver ratio of SHCC in portal phase and equilibrium phase was higher than that in CT. The difference was statistically significant between CT and MRI SHCC in time-density / signal intensity curves (P 0.05). The difference between the two groups was statistically significant (P0.05). There was no significant difference between slow ascending type and basic non-enhancement type. There was no significant difference between CT and MRI SHCC in arterial phase enhancement (P0.05). The display rate of dynamic enhanced SHCC pseudocapsule was higher than that of CT. Conclusion both CT and MRI dynamic enhancement can well reflect the "fast in and out" enhancement mode of SHCC relative to liver parenchyma. MRI has advantages over CT in displaying the characteristics of rapid enhancement in arterial phase of SHCC and false capsule, but CT is more helpful to observe the characteristic of "exit" of SHCC enhancement.
【作者单位】：南通大学附属南通三院影像科;南通大学医学院;北京大学第一医院医学影像科;
【分类号】：R735.7;R730.44;R445.2
【正文快照】： 肝细胞癌(hepatocellular carcinoma,HCC)在我国是最常见的恶性肿瘤之一,提高HCC患者生存率的重要途径是早期诊断和治疗,其中影像特征对HCC的诊断至关重要[1,2]。多排螺旋CT与高场强MRI多期动态增强扫描大大提高了乙肝肝硬化背景小肝癌(small hepatocellular carcinoma,SHCC)

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