热磁对OA兔股骨力学性能影响的研究

发布时间：2018-01-03 05:15

本文关键词：热磁对OA兔股骨力学性能影响的研究　出处：《新疆大学》2015年硕士论文　论文类型：学位论文

【摘要】：目前的治疗骨关节炎的方法很多,其中对于早期患者来说,物理疗法是一种行之有效的方法。但是物理疗法种类多样,治疗的机理也不相同。我们新疆吐鲁番的特色沙疗,经过实践证明有很好的疗效,各种磁疗仪的出现也充分说明了磁疗的治疗效果。我们考虑将这两种方法结合起来,研究其是否能有相互协同的作用,为骨性关节炎的临床理疗提供实验参考。股骨是动物骨骼主要承载骨,所以本文通过分析股骨各骨质层体积的变化及力学性能数据,结合有限元仿真结果,研究沙疗和磁疗作用对患骨性关节炎兔子股骨的影响。本研究采用在新西兰大白兔右侧后腿关节腔注射木瓜蛋白酶的方法建立OA模型,将其分为磁疗组和热磁沙疗组。磁疗组放入自制的磁疗设备中进行治疗,将热磁沙疗组放入磁疗设备中并在股骨周围埋沙进行治疗。利用医学图像处理技术获取股骨各骨质层的体积,通过股骨的力学实验得到相关的力学性能参数,整理和分析骨质层体积和力学实验数据。在实验之后,利用有限元的方法对生物组织的传热及实验环境进行仿真,得出生物组织的热场分布及实验环境的模拟情况。与实验结果对比,数据基本吻合。结果显示股骨的软质骨体积有明显的下降趋势,硬质骨体积有明显的上升趋势。同时,对比磁疗和热磁沙疗的研究数据可以发现,磁疗组硬质骨体积上升的趋势要明显的大于热磁沙疗组,在力学性能方面,磁疗组同样要大于热磁沙疗组。我们从而得出结论,首先磁疗和热磁沙疗对由OA所导致的骨质层变化有很好的缓解作用。其次,我们将磁疗和沙疗结合所采用的这种实验方案,磁疗和沙疗没有达到协同治疗的效果。
[Abstract]:There are many methods to treat osteoarthritis, among which physical therapy is an effective method for early patients, but there are many kinds of physical therapy. The mechanism of treatment is also different. Our characteristic sand therapy in Turpan, Xinjiang, has been proved to have a good curative effect. The appearance of various magnetic therapy devices also fully explains the therapeutic effect of magnetic therapy. We consider combining these two methods to study whether they can have a synergistic effect. The femur is the main bearing bone of animal bone, so this paper analyzes the volume change and mechanical performance data of each bone layer of femur, combined with finite element simulation results. To study the effects of sand therapy and magnetic therapy on femur of rabbits with osteoarthritis, the OA model was established by injecting papain into the right hind leg joint of New Zealand white rabbits. It was divided into magnetic therapy group and thermomagnetic sand therapy group. The magnetic therapy group was treated with self-made magnetic therapy equipment. The thermomagnetic sand therapy group was placed in the magnetic therapy equipment and buried around the femur for treatment. The volume of each bone layer of the femur was obtained by medical image processing technology and the relevant mechanical performance parameters were obtained by the mechanical experiment of the femur. After the experiment, the heat transfer and experimental environment of biological tissue were simulated by finite element method. The thermal field distribution of biological tissue and the simulation of experimental environment were obtained. Compared with the experimental results, the data were basically consistent. The results showed that the volume of soft bone of femur had an obvious downward trend. At the same time, comparing the data of magnetic therapy and magnetic sand therapy, we can find that the increasing trend of hard bone volume in magnetic therapy group is obviously larger than that in thermomagnetic sand therapy group, and the mechanical properties of magnetic therapy group are higher than that of magnetic sand therapy group. Magnetic therapy group is also larger than thermomagnetic sand therapy group. We conclude that first magnetic therapy and thermomagnetic sand therapy have a good effect on the bone layer changes caused by OA. Secondly. The combination of magnetic therapy and sand therapy has failed to achieve synergistic effects.
【学位授予单位】：新疆大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R684.3;R454.1

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