肺癌患者癌因性疲乏与希望水平的相关性研究

发布时间：2018-01-04 02:37

本文关键词：肺癌患者癌因性疲乏与希望水平的相关性研究　出处：《吉林大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:通过对长春市肺癌患者癌因性疲乏(cancer-related fatigue,CRF)与希望水平的调查,了解肺癌患者CRF和希望水平现状;研究一般人口学资料和临床资料对肺癌患者CRF和希望水平的影响;分析肺癌患者CRF和希望水平的相关性;探讨肺癌患者CRF的主要影响因素;根据结果,提出合理的建议与对策,提高肺癌患者的希望水平,从而为降低肺癌患者CRF提供参考依据。方法:采取方便抽样的方法,对长春市三所三级甲等医院的240名肺癌患者进行问卷调查,调查问卷由肺癌患者一般资料调查表、Piper疲乏自我评估修订量表(PFS-R)和Herth希望量表(HHI)三部分组成。运用Epidate3.1资料管理软件对资料进行双录入,采用SPSS13.0统计学软件分析数据。数据采用描述性统计分析、t检验、单因素分析、Pearson相关分析、多元逐步回归分析等统计学方法。结果:1.结果显示,肺癌患者CRF总体得分为5.63±0.902,属于中度疲乏,整体疲乏以中度疲乏为主,占88.7%。在各维度得分情况中,行为疲乏维度平均得分为5.67±0.978,该维度88.2%的患者为中度疲乏;情感疲乏维度平均得分为6.16±1.146,70.9%的患者处于中度疲乏;躯体感知疲乏维度得分最高,为6.93±1.105,61.1%的患者为重度疲乏;认知疲乏维度得分最低,为4.05±1.127,大多数患者处于轻、中度疲乏。2.单因素方差分析显示,肺癌患者CRF在年龄、文化程度、临床分期、治疗手段、有无合并症、有无癌痛及睡眠状况这些方面差异有统计学意义(P0.05)。3.肺癌患者希望总得分为36.22±2.641。在各维度得分中,“对现实和未来的积极态度”平均得分为11.33±0.930;“采取积极的行动”这一维度平均得分为12.37±0.894;“与他人保持亲密的关系”得分最高,平均得分为12.52±1.398。肺癌患者希望总体处于中等以上水平,65%的患者希望位于高等水平。4.单因素方差分析显示,肺癌患者希望水平在年龄、临床分期、有无合并症、有无癌痛及睡眠状况这些方面差异有统计学意义(P0.05)。5.相关分析显示,肺癌患者CRF总分与希望水平呈负相关,且CRF各个维度与希望水平呈负相关。6.多元逐步回归分析显示,希望总分、年龄、临床分期、有无癌痛进入回归方程,是影响肺癌患者CRF的主要影响因素,四者可以解释CRF34.0%的变异(R2=0.340)。希望总分越低,希望水平越低,则CRF越严重;年龄越大,CRF越明显;在临床分期方面,临床分期越严重,CRF总分越高;癌痛感越强,CRF越严重。结论:1.肺癌患者CRF较严重,一般资料中的年龄、文化程度和临床资料中的临床分期、治疗手段、有无合并症、有无癌痛、睡眠状况是肺癌患者CRF的影响因素。2.肺癌患者希望处于中等以上水平,一般资料中的年龄和临床资料中的临床分期、有无合并症、有无癌痛、睡眠状况是肺癌患者希望水平的影响因素。3.肺癌患者CRF总分及各个维度均与希望水平呈负相关。4.希望水平、年龄、临床分期、有无癌痛是肺癌患者CRF的主要影响因素。
[Abstract]:Objective: to Changchun lung cancer patients with cancer-related fatigue (cancer-related fatigue, CRF) investigation and hope level, about CRF of patients with lung cancer and the level of hope status; influence of demographic information and clinical data of patients with lung cancer CRF and hope level of patients with lung cancer; correlation analysis of CRF and the level of hope; to investigate the main influencing factors CRF of patients with lung cancer; according to the results, put forward reasonable proposals and Countermeasures to improve the level of hope, lung cancer patients, so as to provide reference basis for reducing the CRF of patients with lung cancer. Methods: by convenient sampling method, a questionnaire survey was conducted on 240 patients with lung cancer, three Changchun from three hospitals by questionnaire, lung cancer patients questionnaire, self assessment scale (PFS-R) and Piper fatigue Herth Hope Scale (HHI) is composed of three parts. The use of Epidate3.1 data management software for double Input, analysis of data using SPSS13.0 statistical software. The data was analyzed by using descriptive statistical analysis, t test, single factor analysis, Pearson correlation analysis, multiple regression analysis and other statistical methods. The results showed: 1. lung cancer patients, CRF total score was 5.63 + 0.902, belonging to moderate fatigue, overall fatigue to moderate fatigue, accounted for 88.7%. in each dimension, the dimension of fatigue behavior of the average score was 5.67 + 0.978, the 88.2% dimensions were moderate fatigue; emotional fatigue dimension average score was 6.16 + 1.146,70.9% in patients with moderate tired body fatigue; perceived the highest score, 6.93 + 1.105,61.1% in patients with severe cognitive fatigue; fatigue scores lowest that is 4.05 + 1.127, most of the patients in the mild, moderate fatigue.2. single factor variance analysis showed that CRF in patients with lung cancer, age, culture degree, clinical stage, treatment, have No complications, no pain and sleep in these areas have significant difference (P0.05).3. in patients with lung cancer to total score was 36.22 + 2.641. in each dimension score, "the reality and the positive attitude of the future" the average score was 11.33 + 0.930; "take action" this dimension scored an average of 12.37 + 0.894; "and others remain close to" the highest score, the average score was 12.52 + 1.398. in patients with lung cancer overall hope in the moderate level, at the high level of.4. single factor variance analysis showed that 65% of the patients, the level in the age, clinical staging of lung cancer patients have no hope, no complications, pain and sleep status these differences were statistically significant (P0.05).5. correlation analysis showed that the total score of CRF in patients with lung cancer and hope is negatively related to CRF, and the dimensions and the level of hope was negatively related to.6. multivariate regression Analysis shows that the hope scores, age, clinical stage, there is no pain into the regression equation, are main factors affecting the CRF of patients with lung cancer, four can explain the variation in CRF34.0% (R2=0.340). The lower the total score of hope, hope to lower the level of CRF is more serious; the older, the more obvious in clinical CRF; the more serious the staging, clinical staging, higher CRF scores; the stronger sense of pain, more severe CRF. Conclusion: CRF 1. patients with lung cancer is serious, generally in the information age, culture degree and clinical data in clinical staging, treatment, and there is no disease, no pain, sleep is lung cancer patients CRF factors in patients with.2. lung cancer hope in the moderate level, clinical stage in the general information age and clinical data, there are no complications, no pain, sleep is lung cancer patients hope level factors affecting the CRF scores and the.3. of lung cancer patients Each dimension was negatively correlated with hope level,.4. hope level, age, clinical stage, and cancerous pain were the main factors of CRF in patients with lung cancer.

【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R473.73

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