葡萄糖酸氯已定醇预防血液透析中心静脉导管相关感染的研究

发布时间：2018-01-05 02:14

本文关键词：葡萄糖酸氯已定醇预防血液透析中心静脉导管相关感染的研究　出处：《中国消毒学杂志》2016年12期 　论文类型：期刊论文

【摘要】：目的研究葡萄糖酸氯己定醇对血液透析中心静脉导管相关感染的预防效果。方法选择148例留置静脉导管并行血液透析治疗的患者,随机分为实验组和对照组各74例,分别采用20 g/L葡萄糖酸氯己定乙醇溶液和5 000 mg/L的碘伏皮肤消毒液进行穿刺部位消毒和相关护理消毒,比较两组患者及其不同置管部位和置管时间的感染率。结果实验组和对照组感染率分别为10.8%和23.0%。颈内静脉置管组和股静脉置管组感染率分别为11.1%和23.9%,其中实验组感染率分别为9.8%和12.1%,对照组感染率分别为12.5%和35.3%。置管留置时间两周以下,总体感染率为9.4%,实验组和对照组感染率分别为7.1%和11.1%;置管留置时间两周及两周以上,总体感染率提高到19.0%,实验组和对照组感染率分别为11.7%和26.8%。结论采用葡萄糖酸氯己定醇进行血液透析患者中心静脉导管相关感染的防控,其效果优于碘伏。
[Abstract]:Objective to study the preventive effect of chlorhexidine gluconate alcohol on hemodialysis central venous catheter related infection. Methods 148 patients with indwelling venous catheter parallel hemodialysis patients were randomly divided into experimental group and control group with 74 cases in each group, respectively with 20 g/L iodophor solution chlorhexidine gluconate ethanol solution and 5000 mg/L puncture site disinfection and nursing disinfection, were compared between the two groups and different tube position and time of catheter infection rate. The infection rate of experimental group and control group were 10.8% and 23.0%. internal jugular vein catheterization group and femoral vein catheterization group infection rates were 11.1% and 23.9% in the experimental group the infection rates were 9.8% and 12.1% in the control group, the infection rate was 12.5% and 35.3%. respectively the duration of indwelling catheter for two weeks, the overall infection rate was 9.4%, the infection rate of experimental group and control group were 7.1% and 11.1%; catheter retention The overall infection rate increased to 19% after two weeks and two weeks. The infection rates in the experimental group and the control group were 11.7% and 26.8%. respectively. Conclusion the prevention and control of central venous catheter related infections in hemodialysis patients by gluconate and chlorhexidine alcohol is better than iodophor.

【作者单位】：解放军第303医院;移植医学研究院广西重点实验室;
【基金】：中华医院感染控制研究基金(ZHYG2014-0007)
【分类号】：R459.5
【正文快照】： 血液透析是治疗各种原因导致的终末期肾病的有效方法,其中建立能够满足透析条件的通畅血液通路是血液透析顺利完成的关键因素之一〔1〕。中心静脉置管进行透析是目前急性与慢性功能衰竭患者进行血液透析的主要方法,但由于其置管部位的特殊性导致静脉置管感染时有发生〔2〕。据

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