苏州地区14994例儿童呼吸道感染细菌病原学特点

发布时间：2018-01-12 02:00

本文关键词：苏州地区14994例儿童呼吸道感染细菌病原学特点　出处：《中国当代儿科杂志》2016年01期 　论文类型：期刊论文

【摘要】：目的了解儿童呼吸道感染的细菌病原学特点。方法收集2005年11月至2014年10月连续9年因呼吸道感染入住苏州大学附属儿童医院的14994例儿童的病例资料进行回顾性分析。结果 14994份呼吸道感染患儿的痰标本中,细菌培养阳性3947份,总阳性检出率为26.32%。第1位细菌病原为肺炎链球菌(12.79%),其次为流感嗜血杆菌(5.02%)、卡他莫拉菌(2.91%)。在不同年份、不同季节、不同年龄段儿童细菌检出率差异有统计学意义(P0.01)。入院前未使用过抗菌药物的患儿痰细菌培养阳性率高于使用过抗菌药物的患儿(P0.01)。院外病程1个月组、1~3个月组及3个月组患儿痰培养细菌检出率差异有统计学意义(P0.05)。肺炎链球菌、卡他莫拉菌、鲍曼不动杆菌的阳性检出率随病程的延长呈上升趋势(P0.05)。结论肺炎链球菌是引起儿童呼吸道感染的最常见细菌病原,其次为流感嗜血杆菌和卡他莫拉菌。各种细菌在不同的年份、不同的季节、不同的年龄阳性检出率有差异。疾病病程与院外抗菌药物使用对细菌的阳性检出率有影响。
[Abstract]:Objective to investigate the bacterial etiological characteristics of respiratory tract infection in children. Methods 14994 cases of respiratory tract infection admitted to the affiliated Children's Hospital of Suzhou University for 9 years from November 2005 to October 2014 were collected. Retrospective analysis of child case data. Results. 14994 sputum samples were collected from children with respiratory tract infection. The total positive rate of bacterial culture was 26.32. The first bacterial pathogen was Streptococcus pneumoniae 12.79 and the next was Haemophilus influenzae 5.02). In different years, different seasons. The positive rate of sputum bacteria culture in children without antibiotics before admission was higher than that in children who had used antimicrobial agents (P0.01). The course of disease was 1 month group. The detection rate of sputum culture bacteria in the 1-3 month group and 3 month group was significantly different from that in the control group (P 0.05). The positive rate of Acinetobacter baumannii increased with the course of disease. Conclusion Streptococcus pneumoniae is the most common bacterial pathogen causing respiratory tract infection in children. The next is Haemophilus influenzae and Mora Casamora. All kinds of bacteria in different years, different seasons. The positive rate of bacteria was different among different ages. The course of disease and the use of antimicrobial drugs outside hospital had influence on the positive detection rate of bacteria.
【作者单位】：苏州大学附属儿童医院呼吸科;山东大学齐鲁儿童医院呼吸科;
【分类号】：R446.5
【正文快照】： 在世界范围内,呼吸道感染是小儿时期最常见的疾病之一,据WHO统计,呼吸道感染是仅次于早产的导致5岁以下儿童死亡的第二位原因,在发达国家病原体主要为病毒,而发展中国家则以细菌为主[1-2]。2013年儿童社区获得性肺炎管理指南指出,引起儿童社区获得性肺炎的常见病原有细菌、病

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