ICU环境细菌学监测结果与医院感染病原菌耐药谱同源性分析

发布时间：2018-01-16 09:31

本文关键词：ICU环境细菌学监测结果与医院感染病原菌耐药谱同源性分析　出处：《现代预防医学》2016年17期 　论文类型：期刊论文

更多相关文章： 医院感染 环境监测 耐药谱 同源性

【摘要】：目的研究医院感染重点科室环境监测的细菌种类、存在方式与数量,分析与医院感染病原菌之间的同源性。方法收集重症监护室环境细菌学检测标本,进行分离鉴定并录入WHONET软件。应用WHONET软件分析与临床典型病原菌间的耐药谱同源性。结果共收集到环境监测标本1 450例,检出细菌396例,检出率27.3%。存在方式主要集于医务人员手,医疗物体表面。临床标本2 018例,检出菌株987株,检出率48.9%。分离数前5位的是鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌和屎肠球菌,约占总数的65%。环境监测来源的菌株耐药率普遍低于临床菌株。环境菌株耐药谱与在临床菌株耐药谱基本吻合,临床标本菌株耐药谱更为多样化。结论环境菌株与临床菌株存在高比例的耐药谱同源性。手与物表环境应作为医院感染控制的主要环节。医疗环境是外源性医院感染病原菌的主要来源,对侵入性治疗的危急症患者应进行接触隔离治疗。
[Abstract]:Objective to study the species, mode and quantity of bacteria in environmental monitoring of nosocomial infection departments, and to analyze the homology between bacteria and nosocomial infection pathogens. Methods Environmental bacteriological specimens were collected from intensive care unit (ICU). WHONET software was used to analyze the homology of drug resistance spectrum between clinical typical pathogens and WHONET software. Results 1 450 environmental monitoring samples were collected. 396 cases of bacteria were detected, the detection rate was 27.3%. The way of existence was mainly in the hands of medical workers and the surface of medical objects. Clinical specimens were 2018 cases, and 987 strains were detected. The first five isolates were Acinetobacter baumannii Pseudomonas aeruginosa Klebsiella pneumoniae Escherichia coli and Enterococcus faecium. The resistance rate of strains from environmental monitoring sources was generally lower than that of clinical strains. The resistance spectrum of environmental strains was basically consistent with that of clinical strains. Conclusion there is a high proportion homology of drug resistance spectrum between environmental strains and clinical strains. The hand and object surface environment should be the main link of nosocomial infection control, and the medical environment is an exogenous hospital. The main source of pathogenic bacteria. Contact isolation should be performed on critical patients with invasive treatment.
【作者单位】：常熟市医学检验所临床微生物学实验室;
【分类号】：R446.5;R197.32
【正文快照】： 现阶段医院感染已经逐渐成为国内医院中普遍存在的一个重要问题。病人、医务人员及来访者因为和医院医疗环境密切接触后获得的感染,其根本原因在于医院的治疗环境受到了多种病原菌的定植与污染,经各种接触、侵入性医疗手段等过程传染至病患者[1]。医院感染将加重病情及其他并

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