化疗期肺癌患者应对方式与胃肠道反应的相关性

发布时间：2018-01-20 12:48

本文关键词： 应对方式肺癌化疗胃肠道反应　出处：《广东医学》2016年05期 　论文类型：期刊论文

【摘要】：目的探讨化疗期肺癌患者应对方式与胃肠道反应的相关性。方法对120例化疗期肺癌患者分别采用一般情况调查表、医学应对问卷、胃肠道反应评估表进行调查,并对结果进行分析。结果除回避得分与便秘得分、屈服得分与腹泻得分的相关性无统计学意义(P0.05)外,面对、回避得分与患者胃肠反应得分均呈负相关(r值范围-0.419~-0.150,P0.05),而屈服得分与患者胃肠反应得分均呈正相关(r值范围0.156~0.375,P0.05)。进一步多元线性逐步回归分析发现,面对和屈服对患者胃肠道反应的影响有统计学意义(P0.05),分别可解释相应胃肠道反应9.9%~21.9%的变异,屈服对其影响为正性,而面对为负性。结论应对方式与化疗期肺癌患者胃肠道反应密切相关,患者积极地应对有助于减轻胃肠道反应。
[Abstract]:Objective to investigate the correlation between coping style and gastrointestinal reaction in patients with lung cancer during chemotherapy. Methods 120 patients with lung cancer in chemotherapy stage were investigated with general questionnaire and medical response questionnaire. Results except avoidance score and constipation score, yield score and diarrhea score had no statistical significance (P 0.05). There was a negative correlation between avoidance score and gastrointestinal reaction score (r = -0.419? -0.150? P 0.05). There was a positive correlation between the yield score and the gastrointestinal reaction score of the patients, and the range of r value was 0.156 ~ 0.375 (P 0.05). Further multiple linear stepwise regression analysis showed that there was a significant correlation between the yield score and the gastrointestinal reaction score of the patients. The effect of face and yield on gastrointestinal reaction was statistically significant (P 0.05), which could explain the variation of the corresponding gastrointestinal reaction by 9. 9% or 21. 9%, and the effect of yield on it was positive. Conclusion coping style is closely related to gastrointestinal reaction in patients with lung cancer during chemotherapy, and positive coping is helpful to alleviate gastrointestinal reaction.
【作者单位】：安徽医科大学第一附属医院呼吸内科二病区;安徽医科大学护理学院;
【基金】：安徽省高校人文社科研究项目(编号:SK2015A363)
【分类号】：R473.73
【正文快照】： 我国肺癌发病率和病死率全球领先[1],是癌症相关死亡最常见的原因[2],超过75%的患者因转移失去手术机会而选择化疗[3]。恶心、呕吐、便秘、腹泻等被认为是化疗在胃肠道中的主要毒性作用[4],轻者降低患者体质、影响生活质量;严重者可导致电解质紊乱、机体营养失调,从而被迫中断

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