原发性高血压动态动脉硬化指数与颈动脉弹性功能的相关性

发布时间：2018-02-09 15:51

  本文关键词： 原发性高血压 动脉粥样硬化 动态动脉硬化指数 血管回声跟踪技术 颈动脉 弹性　出处：《中国超声医学杂志》2016年11期 　论文类型：期刊论文

【摘要】：目的探讨原发性高血压动态动脉硬化指数与颈动脉弹性功能改变的相关性。方法选择原发性高血压患者104例和对照组健康成人50例,二维超声检测颈动脉内-中膜厚度(IMT),应用血管回声跟踪技术(ET)检测受检者颈总动脉僵硬度、压力应变系数、顺应性、增大指数、单点脉搏传播速度等弹性功能参数,将原发性高血压患者按IMT≥1.0mm者为颈动脉硬化组,1.0mm者为无颈动脉硬化组。通过24h动态血压监测,计算动态动脉硬化指数(AASI)。分析AASI与颈动脉弹性功能参数的相关性。结果原发性高血压患者和对照组动态动脉硬化指数分别为0.56±0.14和0.41±0.12(P0.01);高血压颈动脉硬化组和无颈动脉硬化组动态动脉硬化指数分别为0.59±0.12和0.50±0.11(P0.05);AASI与颈动脉僵硬度、压力应变系数、膨大指数、单点脉搏传导速度呈正相关(r=0.336、0.269、0.274、0.356,均P0.05),与顺应性呈负相关(r=-0.282,P0.01)。与对照组比较,高血压组颈动脉僵硬度指数、压力应变系数、膨大指数、单点脉搏传导速度增大,顺应性降低(P0.05)。结论动态动脉硬化指数可以反映颈动脉硬化及弹性功能改变。原发性高血压动态动脉硬化指数与颈动脉粥样硬化关系密切。
[Abstract]:Objective to investigate the relationship between dynamic arteriosclerosis index and carotid elastic function in patients with essential hypertension. Methods 104 patients with essential hypertension and 50 healthy adults were selected. Carotid intima-media thickness (IMT) was measured by two-dimensional ultrasound, and elastic parameters such as common carotid artery stiffness, pressure strain coefficient, compliance, increase index, pulse velocity at single point were measured by vascular echo tracking technique (ETT). The patients with essential hypertension were divided into carotid atherosclerosis group (IMT 鈮，

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