2014年新疆克拉玛依市健康人群麻疹、风疹抗体水平监测分析

发布时间：2018-02-13 07:04

本文关键词： 麻疹风疹抗体　出处：《现代预防医学》2016年18期 　论文类型：期刊论文

【摘要】：目的了解克拉玛依市人群麻疹、风疹抗体水平,有针对性地开展麻疹、风疹免疫预防工作,有效控制麻疹、风疹的发生和流行,实现消除麻疹的目标。方法按照分层随机抽样方法,采集0~60岁健康人群1 056人份血样,采用ELISA方法,定量检测麻疹抗体、风疹抗体。结果人群麻疹抗体阳性率97.54%、风疹抗体阳性率87.22%,抗体几何平均浓度(Geometric Mean Concentration,GMC)麻疹、风疹分别为:1 220.10 m IU/ml、68.23 IU/ml,不同人群麻疹、风疹抗体阳性率差异均有统计学意义(麻疹χ~2=20.170,风疹χ~2=17.090,P均0.05);不同地区麻疹抗体阳性率在95%以上、保护率在65%~75%之间,风疹抗体阳性率在75%~94%之间,不同地区风疹抗体阳性率差异有统计学意义(χ~2=31.106;P0.001);不同免疫史风疹抗体阳性水平差异有统计学意义(χ~2=30.254,P0.001)。结论克拉玛依市麻疹人群抗体阳性率总体保持在较高水平,风疹抗体阳性率水平略低,乌尔禾区和部分年龄组风疹阳性率较低。应重点加强地区及重点人群疫苗预防接种管理,必要时开展人群查漏补种免疫。
[Abstract]:Objective to understand the antibody level of measles and rubella in the population of Karamay, to carry out the immunization prevention of measles and rubella, and to control the occurrence and prevalence of measles and rubella effectively. Methods according to the stratified random sampling method, 1 056 blood samples were collected from 10 056 healthy people aged 60 years old, and the measles antibody was detected quantitatively by ELISA method. Results the positive rate of measles antibody was 97.54%. The positive rate of rubella antibody was 87.22%. The geometric mean concentration of antibody was geometric Mean Concentration (GMC) measles. The positive rate of rubella antibody was higher than 95%, the protective rate was between 65% and 75%, the positive rate of rubella antibody was between 75% and 94%, the positive rate of rubella antibody was 20. 170%, the positive rate of rubella antibody was 0. 05%, the positive rate of measles antibody was more than 95%, the protective rate was between 65% and 75%, and the positive rate of rubella antibody was between 75% and 94%. The positive rate of rubella antibody was significantly different in different regions (蠂 ~ (2) ~ (2)) (31.106) and rubella antibody (P _ (0.001)) in different immunological history (蠂 ~ (2 +) 30.254 (P 0.001)). Conclusion the positive rate of measles antibody in Karamay is maintained at a high level. The positive rate of rubella antibody was a little lower than that of Wuerhe area and some age groups. The administration of vaccination should be strengthened and the immunization should be carried out if necessary.
【作者单位】：新疆维吾尔自治区克拉玛依市疾病预防控制中心;
【基金】：新疆克拉玛依市科技项目(编号sk2014-54)
【分类号】：R446.6

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