新生儿细菌感染性肺炎的常见菌及耐药性分析

发布时间：2018-02-21 05:00

本文关键词： 新生儿细菌性肺炎致病菌耐药性　出处：《现代预防医学》2016年09期 　论文类型：期刊论文

【摘要】：目的分析医院新生儿细菌性肺炎的常见致病菌及其耐药情况,为临床合理选用抗菌药物,快速有效的控制新生儿细菌性肺炎提供实验依据。方法从医院2013年7月至2015年6月新生儿科送检的痰标本中分离致病菌,采用法国生物梅里埃分司的API系统进行细菌鉴定,K-B法和E-test法进行药物敏感性试验。用Whonet5.6对所有数据进行统计计算。结果从送检的痰标本中共分离出380株细菌,其中大肠埃希菌分离率最高,达35.8%,其次是金黄色葡萄球菌和肺炎克雷伯菌,分别为24.2%和22.6%。其对新生儿常用抗菌药物均产生了一定程度的耐药性。结论大肠埃希菌、金黄色葡萄球菌和肺炎克雷伯菌是引起新生儿细菌性肺炎的常见致病菌,其对常用抗菌药物均产生了一定的耐药性,应当加强检测与控制,并根据药敏试验结果和新生儿抗菌药物的临床使用规范合理选用抗菌药物。
[Abstract]:Objective to analyze the common pathogenic bacteria and their drug resistance of neonatal bacterial pneumonia in hospital, and to select antimicrobial agents reasonably for clinical use. Methods the pathogenic bacteria were isolated from the sputum samples from the hospital from July 2013 to June 2015. The drug sensitivity tests were carried out by using the API system of the French Biomerier Division for bacterial identification by K-B method and E-test method. All the data were statistically calculated by Whonet5.6. Results A total of 380 strains of bacteria were isolated from the sputum samples submitted for examination. The isolation rate of Escherichia coli was the highest (35.8m), followed by Staphylococcus aureus (24.2%) and Klebsiella pneumoniae (22.6). Staphylococcus aureus and Klebsiella pneumoniae are the common pathogens causing neonatal bacterial pneumonia. According to the results of drug sensitivity test and the norms of clinical use of antimicrobial agents in neonates, antimicrobial agents were reasonably selected.
【作者单位】：郑州人民医院检验科;郑州铁路职业技术学院;
【分类号】：R722.135;R446.5

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