光电容积脉搏波无创测量人体血液成分的评估

发布时间：2018-02-28 22:20

本文关键词： 光电容积脉搏波人体无创成分检测血红蛋白白蛋白血糖　出处：《光学精密工程》2016年06期 　论文类型：期刊论文

【摘要】：为了评估光电容积脉搏波法在人体血液主要成分检测方面的精度水平,基于朗伯比尔定律及简化的光电容积脉搏波法测量模型,给出了物质成分测量的极限分辨浓度公式。对公式中的三个要素,即人体测量时的光强信噪比、光程、被测物质的摩尔消光系数进行了评估,获得了理论上光电脉搏波法对血红蛋白、白蛋白、血糖的极限分辨浓度。评估结果表明,光电容积脉搏波法可以测量的血红蛋白、白蛋白和血糖的极限分辨浓度水平分别约为100mg/dL,5000mg/dL以及10 000mg/dL。将该评价结果与现阶段临床需要的检测精度进行对比,可知光电容积脉搏波法能够满足需求,有望实现对血红蛋白的无创检测。
[Abstract]:In order to evaluate the accuracy of photoelectric volumetric pulse wave method in detecting the main components of human blood, based on Lambert's law and simplified photoelectric volumetric pulse wave measurement model, In this paper, the limit resolution concentration formula of material composition measurement is given, and the three elements in the formula, namely, the signal to noise ratio of light intensity, the light path and the molar extinction coefficient of the matter measured, are evaluated. The theoretical limit resolution concentration of hemoglobin, albumin and blood glucose by photo-electric pulse wave method is obtained. The evaluation results show that the photoelectric volumetric pulse wave method can measure hemoglobin, The limit resolution levels of albumin and blood glucose are about 100 mg / dL and 10 000 mg / dL, respectively. Comparing the evaluation results with the current clinical accuracy, we can see that the photoelectric volumetric pulse wave method can meet the demand. It is hoped that the non-invasive detection of hemoglobin will be realized.
【作者单位】：天津大学精密测试技术及仪器国家重点实验室;天津市计量监督检测科学研究院;
【基金】：国家863高技术研究发展计划资助项目(No.2012AA022602) 国家自然科学基金资助项目(No.60938002)
【分类号】：R446.1

【相似文献】