儿科鲍氏不动杆菌感染的危险因素与耐药性研究

发布时间：2018-03-04 17:40

本文选题：儿科　切入点：鲍氏不动杆菌感染　出处：《中华医院感染学杂志》2016年24期 　论文类型：期刊论文

【摘要】：目的调查医院儿科患儿鲍氏不动杆菌感染情况、感染危险因素及耐药性,为儿科鲍氏不动杆菌感染的临床预防治疗提供参考依据。方法选取医院2012年12月-2015年12月儿科收治的患儿3 222例为研究对象,分离、培养并鉴定患儿的病原菌种类,对检出的鲍氏不动杆菌进行药敏试验,数据采用SPSS 19.0软件进行统计分析。结果 3 222例患儿样本中共培养出病原菌471株,以革兰阴性菌为主,共278株占59.02%;鲍氏不动杆菌是最主要的病原菌,占16.56%;机械通气、气管插管、抗菌药物使用时间和导尿管留置是患儿感染鲍氏不动杆菌的危险因素(P0.05);鲍氏不动杆菌对氨曲南的耐药率最高,为97.44%。结论鲍氏不动杆菌是导致儿科感染的最主要病原菌,其对氨曲南的耐药率较高,对亚胺培南的耐药率较低,临床上应根据上述结果指导实施诊治。
[Abstract]:Objective to investigate Acinetobacter baumannii infection, infection risk factors and drug resistance in pediatric children in hospital. Methods 3 222 cases of pediatric patients with Acinetobacter baumannii infection from December 2012 to December 2015 were selected as the research objects, the pathogenic bacteria were isolated, cultured and identified. The drug sensitivity test of Acinetobacter baumannii was carried out, and the data were analyzed by SPSS 19.0 software. Results 471 strains of pathogenic bacteria were cultured in 3 222 children, mainly Gram-negative bacteria. A total of 278 strains accounted for 59.02; Acinetobacter baumannii was the main pathogen, accounting for 16.56; mechanical ventilation, tracheal intubation, The time of use of antimicrobial agents and indwelling catheter were the risk factors for infection of Acinetobacter baumannii in children (P 0.05), and Acinetobacter baumannii had the highest resistance rate to aztreonam, which was 97.44%. Conclusion Acinetobacter baumannii is the main pathogen causing pediatric infection. The drug resistance rate to aztreonam was higher than that to imipenem, so the diagnosis and treatment should be guided by the above results.
【作者单位】：南阳医学高等专科学校第一附属医院儿科;南阳医学高等专科学校基础部;
【基金】：河南省科技厅科技发展计划(14A320012)
【分类号】：R446.5;R725.1

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