北京市某三甲医院输血不良反应回顾性分析

发布时间：2018-03-13 05:26

本文选题：输血不良反应　切入点：成分输血　出处：《中国输血杂志》2016年02期 　论文类型：期刊论文

【摘要】：目的通过分析临床输血不良反应的特征和机制,增强未来对不良反应的预防和应对能力。方法 2012年1月-2014年12月日查阅本院所有输血记录、输血不良反应患者病历,分析不良反应发生的性质、特征、概率和机制。结果输血不良反应率为0.43%(33/7 673)。不良反应最常见的是过敏反应,占72.7%(24/33),其次为非溶血性发热反应,占24.2%(8/33),不良反应率呈逐年下降趋势,分别为0.53%(14/2 646)、0.41%(10/2 449)和0.35%(9/2 578)。3年内输注血制品共49 674袋,其中悬浮红细胞、单采血小板和新鲜冰冻血浆的不良反应发生率分别为0.48%(10/2 067)、0.08%(6/7 251)和0.07%(16/21 925),明显高于其他血液成分。发生不良反应的患者以干部保健一病区14.8%(4/27)和重症监护室4.9%(5/102)居多。老年、有输血史、孕产史的患者容易发生不良反应。结论本院输血不良反应总体发生率较低;提倡少白细胞血制品的应用;老年、有输血史、孕产史、重症患者输血要特别预防和监测;应完善不良反应回报制度,安全输血。
[Abstract]:Objective to analyze the characteristics and mechanisms of adverse reactions of blood transfusion in order to enhance the prevention and coping ability of adverse reactions in the future. Methods from January 2012 to December 2014, all blood transfusion records and medical records of patients with adverse reactions of blood transfusion were reviewed. The characteristics, probability and mechanism of adverse reactions were analyzed. Results the adverse reaction rate of blood transfusion was 0.43 / 7 773%. The most common adverse reactions were allergic reactions, accounting for 72.7% of 33%, followed by non-hemolytic fever, accounting for 24.2g / 833%. The adverse reaction rate showed a decreasing trend year by year. They were 0.53 / 26460.41% 10 / 2449) and 0.35% 9 / 2578% respectively. In three years, 49,674 bags of blood products were infused, of which the suspended red blood cells, The incidences of adverse reactions of platelets and fresh frozen plasma were 0.48 / 10 / 20 67 / 0.08 and 0.07 / 7 251, respectively, which were significantly higher than those of other blood components. Conclusion the incidence of adverse reactions of transfusion in our hospital is low, the application of oligoleucocyte blood products should be advocated, the elderly, the history of blood transfusion, the history of pregnancy and childbirth, and the blood transfusion of severe patients should be specially prevented and monitored. The system of adverse reaction return should be improved and blood transfusion should be safe.
【作者单位】：中日友好医院输血科;中日友好医院检验科;
【分类号】：R457.13

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