肾病型肠内营养制剂在维持性血液透析并发营养不良病人中的疗效分析

发布时间：2018-03-16 16:48

本文选题：肾病型肠内营养制剂　切入点：维持性血液透析　出处：《肠外与肠内营养》2016年05期 　论文类型：期刊论文

【摘要】：目的:观察肾病型肠内营养(EN)制剂在改善维持性血液透析(MHD)并发营养不良病人营养状态的有效性。方法:选取MHD并发营养不良的病人80例,随机分为观察组和对照组。病人在常规血液透析基础上(2~3次/周),观察组应用肾病型EN制剂治疗6个月,对照组给予单纯饮食指导。分别于营养治疗开始、3个月和结束时观察两组病人的主观综合营养评估(SGA),人体成分分析指标(体重、肌肉、蛋白质、脂肪、水分和BMI),生化指标(血清清蛋白、前清蛋白、肌酐、尿素)和透析充分性指标尿素清除率(Kt/V)等。结果:病人营养治疗后SGA、体重、肌肉、蛋白质、脂肪、水分、BMI、清蛋白、前清蛋白较治疗前明显升高(P0.05);血肌酐、尿素和Kt/V治疗前后无显著性差异(P0.05)。观察组病人SGA、体重、肌肉、蛋白质、脂肪、BMI、清蛋白和前清蛋白较对照组升高,两组间比较有显著性差异(P0.05);而血肌酐、尿素、水分和Kt/V无显著性差异(P0.05)。结论:肾病型肠内营养制剂可有效地改善维持性血液透析合并营养不良病人的营养状况。
[Abstract]:Objective: to observe the effect of enteral nutrition (en) preparation of nephrotic type on improving the nutritional status of patients with maintenance hemodialysis (HD) complicated with malnutrition. Methods: 80 patients with MHD complicated with malnutrition were selected. The patients were divided into observation group and control group at random. The patients were treated with nephrotic en for 6 months on the basis of routine hemodialysis. The control group was given simple dietary guidance. The subjective comprehensive nutrition assessment of the two groups was observed at the beginning, three months and the end of nutritional therapy. The body composition analysis indexes (body weight, muscle, protein, fat, body weight, muscle, protein, fat) were measured. Water and BMIA, biochemical indexes (serum albumin, prealbumin, creatinine, urea) and dialysis adequacy index, urea clearance rate (KT / V). Results: SGA, body weight, muscle, protein, fat, moisture, BMIs, albumin, etc. Serum creatinine, urea and Kt/V had no significant difference before and after treatment. SGA, body weight, muscle, protein, fat BMI, albumin and prealbumin in the observation group were higher than those in the control group. There was significant difference between the two groups (P 0.05), but there was no significant difference in serum creatinine, urea, water and Kt/V. Conclusion: Nephrotic enteral nutrition preparation can effectively improve the nutritional status of maintenance hemodialysis patients with malnutrition.
【作者单位】：天津市第五中心医院营养科;
【分类号】：R459.3;R459.5

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