连续血液净化系统中实时监测模块的研究

发布时间：2018-03-28 08:15

本文选题：连续血液净化　切入点：实时监测　出处：《中国科学院研究生院(长春光学精密机械与物理研究所)》2015年硕士论文

【摘要】：近年来,人们的生活节奏和工作压力随着经济的快速发展逐年递增,身体素质由于长期缺乏锻炼而逐渐下降。人们呼吸及消化系统的功能也随着生活环境的污染而不断退化,有越来越多的人被确诊为急慢性肾功能疾病,而且患者有向年轻化发展的趋势。许多疾病都与血浆内源性或外源性毒素浓度增加相关联。因此,从血液循环中除去废物或毒素是对这些疾病的治疗方法之一。在体外循环设备运行过程中,需要对体外循环管路内的血液温度、血压及血氧饱和度进行测量,实时监测人体的生理状态,能够给医师治疗提供参考数据。同时,防止循环管路堵塞或者流通不畅,如果发生意外情况,立即报警并采取相应急救措施。因此,连续血液净化系统需要对系统中血液温度、血压和血氧饱和度进行实时监测。本文旨在设计三个监测模块,温度监测模块、血压监测模块和血氧饱和度测量模块,分别对体外循环管路内的血液温度、血压和血氧饱和度进行实时监测。监测模块的设计是以MSP430单片机为核心,以MLX90614红外温度传感器、NPC-1220气压传感器和宽谱硅光电池作为信号检测单元,分别检测循环管路中血液温度、血压和血氧饱和度,并将检测得到的信号经过放大滤波处理后,在MSP430单片机中计算处理,并将血液温度值、血压值和血氧饱和度值通过LCD显示屏显示。实验表明,本文设计的连续血液净化系统中实时监测模块功耗低,具有较好的抗干扰能力和较高的测量精度。同时实时监测模块采用的都是非侵入式测量,因此在保证测量精度的基础上,避免了由于同血液接触而造成感染。
[Abstract]:In recent years, people's rhythm of life and work pressure is increasing year by year with the rapid development of economy, because of the long-term lack of exercise and physical quality decreased gradually. The people of respiratory and digestive system function with living environment pollution and degradation, there are more and more people have been diagnosed as acute or chronic renal disease, and patients with development to the young trend. Many diseases are associated with plasma endogenous or exogenous toxin concentration is associated with increased. Therefore, from blood circulation to remove waste or toxins is one of the treatments for these diseases. In cardiopulmonary bypass equipment during the operation, the need for extracorporeal circulation pipe in blood temperature, blood pressure and oxygen saturation. Measurement, real-time monitoring of human physiological state, it can provide the reference data for medical treatment. At the same time, to prevent the circulation pipeline blockage or poor circulation, if the accident situation, The police immediately and take appropriate emergency measures. Therefore, continuous blood purification system to the temperature of the blood system, blood pressure and oxygen saturation monitoring. This paper aims to design three monitoring module, temperature monitoring module, blood pressure monitoring module and oxygen saturation measurement module, respectively for extracorporeal circulation pipe in blood temperature, blood pressure and oxygen the saturation of the real-time monitoring, monitoring module is designed with MSP430 MCU as the core, using MLX90614 infrared temperature sensor, NPC-1220 pressure sensor and a wide spectrum of silicon photocell as the signal detection unit, respectively, the temperature of the blood circulation pipeline, blood pressure and oxygen saturation, and the detected signal after amplifying and filtering processing, computing process MSP430 microcontroller, and the blood temperature, blood pressure and oxygen saturation value through the LCD display. The experimental results show that this design The continuous blood purification real-time monitoring module in the system of low power consumption, the measurement precision has good anti-jamming capability and high real-time monitoring module. At the same time are used in non intrusive measurement, so the precision and avoid the same blood contact caused by infection.

【学位授予单位】：中国科学院研究生院(长春光学精密机械与物理研究所)
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R459.5

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