青年人群臂踝动脉脉搏波传导速度、颈动脉内膜中层厚度和血流介导的血管舒张功能的相关性

发布时间：2018-03-30 23:09

  本文选题：青年人群　切入点：臂踝动脉脉搏波传导速度　出处：《中华高血压杂志》2016年04期

【摘要】：目的探讨青年人群臂踝动脉脉搏波传导速度(baPWV)、颈动脉内膜中层厚度(IMT)和血流介导的血管舒张功能(FMD)的相关性。方法对陕西汉中老君乡10个自然村人群心血管病危险因素进行调查,选取其中完成IMT、FMD、baPWV 3项检查,符合入排标准的30~45岁青年人群473名进行体格及生化指标检查。BP-203RPEⅢ动脉硬化检测仪测量baPWV,超声检测IMT和FMD。应用Pearson相关和多元线性回归分析baPWV与IMT、FMD的相关性。结果与男性相比,女性FMD值较高[(10.28±4.25)%比(9.38±4.40)%,P0.05],baPWV值较低[(12.26±2.05)m/s比(13.59±1.96)m/s,P0.01],两者IMT水平差异无统计学意义。Pearson相关分析结果显示,IMT与FMD、baPWV的相关性无统计学意义,FMD和baPWV则呈负相关(r=-0.35,P0.01)。多元线性回归分析校正性别、年龄、收缩压、舒张压、体质量指数、腰臀比、三酰甘油、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、空腹血糖、血肌酐、血尿酸等心血管病相关因素后,发现FMD是baPWV的影响因素(B=-8.689,P0.01)。结论在本组青年人群中,baPWV和FMD呈负相关,而IMT与baPWV及FMD均无相关性。
[Abstract]:Objective to investigate the correlation between brachial malleolus pulse wave velocity (PWV), carotid intima-media thickness (IMT) and blood flow mediated vasodilation (FMD) in young people.Methods the risk factors of cardiovascular disease in 10 natural villages in Laojun Township, Hanzhong, Shaanxi Province were investigated, and three items of IMT FMDA PWV were selected.A total of 473 young people aged 30 to 45 years old who met the admission criteria were examined with physical and biochemical indexes. The baPWV was measured by BP-203 RPE 鈪，

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