2012-2015年襄阳市中心医院金黄色葡萄球菌耐药监测分析

发布时间：2018-04-04 04:43

本文选题：金黄色葡萄球菌　切入点：临床分布　出处：《现代预防医学》2016年22期

【摘要】：目的了解某院2012-2015年金黄色葡萄球菌的临床分布特征及对抗菌药物的耐药特点,为临床合理使用抗菌药物提供理论依据。方法采用WHONET5.6对724株金黄色葡萄球菌的标本来源、科室分布及耐药性等进行统计分析。结果 2012-2015年该院从送检的67 262份标本中分离出724株金黄色葡萄球菌,其科室分布主要以ICU、骨科、皮肤科、普外科、神经外科和肾病科为主;标本来源主要为分泌物,其次来源于痰液、血液、脓液和脑脊液;其中共检出耐甲氧西林金黄色葡萄球菌(MRSA)268株,检出率为37.0%(268/724);金黄色葡萄球菌对阿奇霉素、克林霉素、克拉霉素、红霉素和青霉素的耐药率高达70.0%。结论该院检出的金黄色葡萄球菌对多种抗菌药物均可产生不同程度的耐药性,故应加强临床合理使用抗菌药和感染控制的监管。
[Abstract]:Objective to investigate the clinical distribution and antimicrobial resistance of Staphylococcus aureus in a hospital from 2012 to 2015 so as to provide a theoretical basis for the rational use of antibiotics in clinic.Methods WHONET5.6 was used to analyze the origin, distribution and drug resistance of 724 strains of Staphylococcus aureus.Results 724 strains of Staphylococcus aureus were isolated from 67,262 specimens from 2012 to 2015. ICU, orthopedics, dermatology, general surgery, neurosurgery and renal diseases were the main distribution of Staphylococcus aureus, and the samples were mainly derived from secretions.The next source was sputum, blood, pus and cerebrospinal fluid. A total of 268 strains of methicillin-resistant Staphylococcus aureus MRSA were detected, with a detection rate of 37.0% 268 / 724; Staphylococcus aureus against azithromycin, clindamycin, clarithromycin, and clarithromycin.The resistance rates of erythromycin and penicillin were as high as 70.0.Conclusion Staphylococcus aureus detected in our hospital has different degree of drug resistance to various antimicrobial agents, so we should strengthen the supervision of rational use of antimicrobial agents and infection control in clinic.
【作者单位】：襄阳市中心医院/湖北文理学院附属医院医学检验部;
【基金】：湖北省卫生计生科研基金资助(WJ2015XB019) 湖北省襄阳市科技局基金项目资助(襄科计2014-9)
【分类号】：R446.5

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