中国大陆地区新生儿院内感染病原体分布的系统评价

发布时间：2018-04-17 21:27

本文选题：婴儿 + 新生　；参考：《重庆医学》2016年03期

【摘要】：目的采用循证分析的方法系统评价我国大陆地区新生儿院内感染病原体分布情况,为临床控制新生儿医院感染提供更好的科学依据。方法全面系统检索中国知网(CNKI)、中国生物医学文献服务系统(CBM)、维普(VIP)、万方数据库(WanFang)及PubMed。对文献进行筛选,使用Excel软件提取数据,运用Comprehensive Meta Analysis软件进行率的合并计算,根据异质性检验结果选择合适模型。结果研究共纳入68篇合格文献,新生儿院内感染最常见病原体为葡萄球菌属[32%(95%CI:27%~37%)]、沙门菌属[32%(95%CI:0%~68%)]。亚组分析显示:三级和二级及以下等级医院新生儿院内感染最常见病原体均为葡萄球菌;专科医院最常见病原体为葡萄球菌属,综合性医院最常见病原体为沙门菌属;东部地区医院最常见病原体为沙门菌属,中部和西部地区医院最常见病原体均为葡萄球菌属;1985~1999年最常见病原体为葡萄球菌属,2000~2012年最常见病原体为病毒。结论新生儿院内感染最常见病原体为葡萄球菌属。
[Abstract]:Objective to evaluate the distribution of pathogens of neonatal nosocomial infection in mainland China and provide a better scientific basis for clinical control of nosocomial infection.Methods CNKI, CBMN, VIPV, WanFangand PubMed. were searched systematically.The literature was screened, the data was extracted by Excel software, the rate was calculated by Comprehensive Meta Analysis software, and the appropriate model was selected according to the results of heterogeneity test.Results the most common pathogens of nosocomial infection in neonates were Staphylococcus and Salmonella.The subgroup analysis showed that the most common pathogens of nosocomial infection of neonates were Staphylococcus, the most common pathogens in specialized hospitals were Staphylococcus, and the most common pathogens in general hospitals were Salmonella.Salmonella is the most common pathogen in eastern hospitals, and Staphylococcus is the most common pathogen in central and western hospitals from 1985 to 1999. The most common pathogen is Staphylococcus from 2000 to 2012.Conclusion the most common pathogen of neonatal nosocomial infection is Staphylococcus genus.
【作者单位】：重庆医科大学公共卫生与管理学院/医学与社会研究中心/健康领域社会风险预测治理协同创新中心;中国人民解放军324医院普外科;
【基金】：国家自然科学基金资助项目(31071093、31170129、31200064)
【分类号】：R446.5

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