炎性因子检测对颅内感染早期诊断的临床应用研究

发布时间：2018-04-19 13:01

本文选题：炎性因子 + 颅内感染　；参考：《中华医院感染学杂志》2016年16期

【摘要】：目的探讨炎性因子检测对颅内感染早期诊断的应用价值,为颅内感染早期诊断、减少患者并发症提供参考依据。方法选取2013年6月-2015年6月医院行开颅手术感染患者40例为试验组,同期选择术后未发生颅内感染40例患者做为对照组;比较两组患者炎性因子,数据采用SPSS 19.0软件进行统计分析。结果试验组患者血清C-反应蛋白(CRP)、降钙素原(PCT)、肿瘤坏死因子(TNF-α)及一氧化氮(NO)表达水平分别为(41.38±4.23)mg/L、(5.69±1.05)μg/L、(6.87±0.94)ng/L及(25.94±3.54)μmol/L,均高于对照组,差异有统计学意义。结论 PCT、CRP、TNF-α及NO可特异性反应患者是否感染及感染程度,在颅内感染早期诊断中具有较高的应用价值,值得临床推广。
[Abstract]:Objective to explore the application value of inflammatory factor detection in early diagnosis of intracranial infection, and to provide reference for early diagnosis of intracranial infection and reduction of complications.Methods from June 2013 to June 2015, 40 patients with craniotomy infection were selected as experimental group and 40 patients without intracranial infection as control group.The data were analyzed by SPSS 19.0 software.Results the levels of serum C-reactive protein (CRP), procalcitonin (PCT), tumor necrosis factor TNF- 伪 (TNF- 伪) and nitric oxide (no) in the experimental group were 41.38 卤4.23 mg / L, 5.69 卤1.05 渭 g / L, 6.87 卤0.94)ng/L and 25.94 卤3.54 渭 mol / L, respectively, which were significantly higher than those in the control group (P < 0.05).Conclusion PCT TNF- 伪 and no can specifically reflect whether the patients are infected or not and the degree of infection. It has a high application value in the early diagnosis of intracranial infection and is worth popularizing in clinic.
【作者单位】：新乡医学院第三附属医院检验科;新乡医学院第三附属医院脑外科;新乡医学院药学院药理学教研室;新乡医学院第三附属医院普外科;
【基金】：河南省卫生厅重点基金资助项目(LX20071004)
【分类号】：R651.1;R446.1

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