糖尿病患者肺部感染的病原学与耐药性研究

发布时间：2018-04-23 08:45

本文选题：肺部感染 + 糖尿病　；参考：《中华医院感染学杂志》2016年02期

【摘要】：目的调查住院糖尿病患者肺部感染的病原学与耐药性,总结干预措施,为该病的早期治疗提供参考依据。方法选取2014年1-12月医院收治的118例糖尿病发生肺部感染患者为研究对象,采集患者的痰标本,分析病原菌分布构成及其耐药性。结果共分离出病原菌120株,其中革兰阴性菌74株占61.7%,革兰阳性菌32株占26.7%,真菌14株占11.6%;鲍氏不动杆菌对妥布霉素耐药率为0,肺炎克雷伯菌对阿米卡星、亚胺培南耐药率为0,铜绿假单胞菌对呋喃妥因、妥布霉素耐药率为0,大肠埃希菌对呋喃妥因、美罗培南、亚胺培南耐药率为0,金黄色葡萄球菌及表皮葡萄球菌对呋喃妥因耐药率均为0,真菌中白色假丝酵母菌无耐药菌检出。结论肺炎克雷伯菌是糖尿病患者发生肺部感染最常见的病原菌,病原菌的总体耐药性不容乐观,对患者应采取综合干预措施,合理应用抗菌药物。
[Abstract]:Objective to investigate the etiology and drug resistance of pulmonary infection in hospitalized diabetic patients, and to summarize the intervention measures to provide reference for the early treatment of the disease. Methods 118 patients with diabetes in the hospital in 1-12 months of 2014 were selected as the research object, the sputum standard of the patients was collected, the distribution of pathogenic bacteria and their drug resistance were analyzed. There were 120 strains of pathogenic bacteria, of which 74 were gram-negative, 32 were gram-positive, 14 were 11.6%, and the resistance rate of Acinetobacter baumannii to tobramycin was 0, Klebsiella pneumoniae was resistant to Amikacin, imipenem, 0, Pseudomonas aeruginosa, and tobramycin, and 0, Escherichia coli. The resistance rate of fururdine, meropenem and imipenem was 0. The resistance rate of Staphylococcus aureus and Staphylococcus epidermidis to fururdine was 0, and Candida albicans was found in fungi. Conclusion Klebsiella pneumoniae is the most common pathogen of lung infection in diabetic patients, and the overall resistance of pathogenic bacteria is not optimistic. The patients should take comprehensive intervention measures and rational use of antibiotics.

【作者单位】：聊城市第三人民医院内科;
【基金】：山东省科技厅基金资助项目(201209014)
【分类号】：R446.5

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