输血前感染性指标检测对患者输血感染的影响研究

发布时间：2018-04-23 10:48

本文选题：输血前 + 感染性指标　；参考：《中华医院感染学杂志》2016年13期

【摘要】：目的探讨输血前感染性指标检测对输血感染的影响,为临床血液病感染的预防控制及减少医疗纠纷提供参考。方法选择2012年6月-2015年6月于医院拟接受输血1 300例患者进行输血前感染性指标检测,包括乙型肝炎病毒五项标志物、丙型肝炎病毒(HCV)、苍白密螺旋体(抗-TP)、人类免疫缺陷病毒(HIV);采用酶免疫分析法对所有患者进行输血前8项检测,以了解患者输血前的感染情况。结果在输血感染性指标检测中HBsAb的阳性率最高占21.69%,其次为HBsAg占10.85%。患者存在2种或3种重叠感染模式,其中以HBsAb+HBeAb的重叠感染模式所占比例最高共26例占2.00%,其次为HBsAg+HBsAb+HBcAb的重叠感染模式,共24例占1.85%。不同年龄段患者HBsAg、HBsAb、HBeAg、HBeAb、HBcAb阳性率比较差异有统计学意义(P0.05)。结论加强对输血前7项感染性指标的检测不仅提高患者的输血安全性、发现潜在疾病,还能降低院内交叉感染以及医疗纠纷的发生,在临床上具有重要意义。
[Abstract]:Objective to investigate the influence of pretransfusion infection index on blood transfusion infection, and to provide reference for prevention and control of clinical hematologic infection and reduction of medical disputes. Methods from June 2012 to June 2015, 1,300 patients were selected to receive blood transfusion, including five markers of hepatitis B virus (HBV). Hepatitis C virus (HCV), anti-TPV (human immunodeficiency virus) and HIV-1 were detected by enzyme immunoassay (Elisa) in all patients before blood transfusion in order to understand the infection of patients before blood transfusion. Results the positive rate of HBsAb was the highest in blood transfusion infection index, followed by HBsAg. There were two or three kinds of superinfection modes in the patients, of which 26 cases (2.00%) were the highest in HBsAb HBeAb, and the next was HBsAg HBsAb HBcAb (1.85%). There was significant difference in the positive rate of HBcAb of HBeAg + HBeAb-HBeAb-HBeAb-HBeAb in patients of different age groups (P 0.05). Conclusion strengthening the detection of 7 infectious indexes before blood transfusion can not only improve the safety of blood transfusion, discover latent diseases, but also reduce the occurrence of hospital cross infection and medical disputes, which is of great significance in clinical practice.
【作者单位】：金华市人民医院输血科;
【基金】：浙江省卫生厅基金资助项目(ZJ291223)
【分类号】：R457.1

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