给氧负压伤口治疗在骨科慢性伤口中的可行性研究

发布时间：2018-05-03 21:31

  本文选题：慢性伤口 + 负压伤口治疗　； 参考：《实用骨科杂志》2016年12期

【摘要】：目的评价负压伤口治疗联合局部给氧对骨科慢性伤口的可行性及效果。方法对60例骨科创伤性慢性伤口患者随机分为两组,每组30例,对照组给予负压伤口治疗,连续10d。观察组在负压伤口治疗基础上联合局部给氧2L/min,干预时间同对照组,观察指标:2组治疗0d和10d监测伤口渗液pH、温度、PUSH愈合计分、肉芽组织覆盖率、伤口达到植皮条件所需时间、植皮成活率、愈合时间、治愈率。结果治疗10d后,观察组伤口渗液pH(7.22±0.16),低于对照组(7.50±0.26)(P0.01)。达到植皮条件所需时间(12.65±7.16)d,低于对照组(18.28±8.85)d,伤口床的温度(34.02±0.41)℃,高于对照组(33.25±0.35)℃(P0.01)。观察组肉芽组织覆盖率(34.30±2.83)%高于对照组(27.27±3.54)%(P=0.00)。植皮成活率(93.22±1.91)%,高于对照组(83.21±1.86)%(P=0.00)。压疮愈合计分量表(pressure ulcer scale for healing,PUSH)计分结果差异无统计学意义(P0.05)。所有患者随访3个月,观察组治愈率为86.67%(26/30),平均愈合时间为(35±15.5)d,对照组治愈率为53.33%(16/30),平均愈合时间为(49±23.4)d,差异有统计学意义(P0.05)。结论将负压伤口治疗与局部给氧联合应用于骨科慢性伤口能促进伤口愈合及肉芽组织生长,方法可行,效果优于单纯负压治疗。
[Abstract]:Objective to evaluate the feasibility and effect of negative pressure wound treatment combined with local oxygen on chronic orthopedic wound. Methods 60 cases of traumatic chronic wound in orthopedic department were randomly divided into two groups, 30 cases in each group. The control group was treated with negative pressure wound for 10 days. The observation group combined with local oxygen 2L / min on the basis of negative pressure wound treatment, the intervention time was the same as that of the control group. The observation index was: 0 d and 10 d after treatment, the pH of wound exudate, the temperature of pressure healing, the granulation tissue coverage rate, the time needed for the wound to reach the condition of skin grafting were monitored. Survival rate, healing time and cure rate of skin graft. Results after 10 days of treatment, the pH(7.22 卤0.16m of wound effusion in the observation group was lower than that in the control group (7.50 卤0.26). The time required to reach the condition of skin grafting was 12.65 卤7.16 days, which was lower than that of the control group (18.28 卤8.85) days. The temperature of the wound bed was 34.02 卤0.41 鈩，

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