持续性躯体形式疼痛障碍局部一致性脑功能磁共振研究

发布时间：2018-05-16 19:05

  本文选题：持续性躯体形式疼痛障碍 + 局部一致性　； 参考：《重庆医学》2016年31期

【摘要】：目的采用静息态功能磁共振局部一致性(ReHo)技术,观察持续性躯体形式疼痛障碍(PSPD)患者脑局部ReHo值。方法纳入21例以头痛为主要症状的PSPD患者和17例年龄、性别相匹配的健康对照者,所有被试者行静息态功能磁共振,对磁共振数据进行分析得到ReHo结果,然后对比PSPD患者组与健康对照组的差异。结果与健康对照组比较,PSPD患者双侧额叶ReHo值升高,而双侧枕叶、双侧直回、右侧小脑后叶、右侧中央旁小叶、左侧颞中回ReHo值降低(P0.01)。结论PSPD患者相关脑区神经元活动一致性存在改变,这种改变可能是导致PSPD患者发病的相关因素之一。
[Abstract]:Objective to observe the regional ReHo of patients with persistent somatoform pain disorder (SPD) by resting functional magnetic resonance imaging (MRI). Methods Twenty-one patients with PSPD with headache as the main symptom and 17 healthy controls with age and sex matched underwent resting functional magnetic resonance imaging (fMRI). The results of ReHo were analyzed. Then the difference between PSPD group and healthy control group was compared. Results compared with the control group, the ReHo value of bilateral frontal lobe in patients with PSPD increased, while the ReHo value of bilateral occipital lobe, bilateral straight gyrus, right posterior cerebellar lobe, right paracentral lobe and left middle temporal gyrus decreased P0.01. Conclusion there is a change in neuronal activity consistency in PSPD patients, which may be one of the related factors leading to the pathogenesis of PSPD.
【作者单位】： 第三军医大学西南医院神经内科;第三军医大学西南医院放射科;第三军医大学护理学院心理教研室;
【分类号】：R402
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本文编号：1898053