重症监护病房患者多重耐药菌定植情况及其危险因素分析

发布时间：2018-05-18 05:50

  本文选题：多重耐药菌(MDROs) + 定植　； 参考：《中国公共卫生》2016年11期

【摘要】：目的了解重症监护病房(ICU)患者多重耐药菌(MDROs)定植情况及其危险因素,为MDROs的预防和控制提供参考依据。方法整群抽取东南大学附属中大医院2014年1月—2015年12月ICU收治的1143例患者进行病例收集,并采集其鼻前庭及咽拭子进行细菌培养和药敏试验。结果 ICU中1 143例患者发生MDROs定植者217例,MDROs定植发生率为18.99%;217例MDROs定植者中,发生多重耐药金黄色葡萄球菌定植者27例(12.44%),多重耐药肺炎克雷伯菌定植者122例(56.22%),多重耐药鲍曼不动杆菌定植者41例(18.89%),多重耐药铜绿假单胞菌定植者27例(12.44%);多因素非条件logistic回归分析结果显示,入ICU前抗菌药物使用种类2种(OR=2.011,95%CI=1.081~4.552)和入ICU前抗菌药物使用时间≥3d(OR=4.201,95%CI=2.108~5.011)是ICU患者M DROs定植发生的危险因素。结论 ICU患者M DROs定植发生率较高,以多重耐药肺炎克雷伯菌定植为主;入ICU前抗菌药物使用种类较多和入ICU前抗菌药物使用时间较长是ICU患者MDROs定植发生的主要危险因素。
[Abstract]:Objective to investigate the colonization and risk factors of multidrug resistant bacteria (MDR) in patients with ICU in intensive care unit (ICU), and to provide reference for the prevention and control of MDROs. Methods 1143 patients admitted to ICU from January 2014 to December 2015 were collected by cluster sampling and their nasal vestibule and throat swabs were collected for bacterial culture and drug sensitivity test. Results the incidence of MDROs colonization in 1 143 cases of ICU was 18. 99%, and the incidence of MDROs colonization was 18. 99% in 217 cases of MDROs colonization. There were 27 cases of multidrug resistant Staphylococcus aureus colonization, 122 cases of multidrug resistant Klebsiella pneumoniae colonization, 41 cases of Acinetobacter baumannii colonization, 27 cases of multidrug resistance Pseudomonas aeruginosa colonization 12.4444 and 27 cases of multidrug resistant Pseudomonas aeruginosa colonization. The results of non-conditional logistic regression analysis showed that, The risk factors of M DROs colonization in ICU patients were two kinds of antimicrobial agents used before ICU (2.0111195) and before ICU (鈮，

本文编号：1904667