低效价不规则抗体与红细胞输注无效的分析

发布时间：2018-06-04 00:32

本文选题：红细胞 + 无效输注　；参考：《中国输血杂志》2016年04期

【摘要】：目的调查南阳地区患者输注红细胞的临床病例,选取其中输血无效者,分析红细胞无效输注与低效价不规则抗体的漏检的相关性。方法选取在本市中心医院输注红细胞无效治疗患者570例,对患者血样用血清学试验重新分析检测是否存在低效价不规则抗体的漏检。结果红细胞输注无效患者570例(12.5%)中,女性比较男性χ2=36.81,P0.01;有输血史与无输血史患者比较χ2=619.6,P0.01;有妊娠史与无妊娠史患者比较χ2=85.5,P0.01。因低效价不规则抗体漏检引起的输注无效71例,占红细胞输注无效的12.4%。结论南阳地区患者红细胞输注无效与低效价不规则抗体的漏检密切相关,低效价不规则抗体与患者输血史、妊娠史、输血次数、妊娠次数密切相关,我们常规的聚凝胺法容易漏检低效价的不规则抗体,用低效价的阳性对照试剂作对照以及改良聚凝胺法与抗球蛋白法联合检测可以提高检出率,避免该类患者因低效价不规则抗体漏检而导致无效输注。
[Abstract]:Objective to investigate the clinical cases of red blood cells infusions to patients in Nanyang, and to select the ineffective transfusion of blood transfusion in Nanyang, and to analyze the correlation between the ineffective infusion of red blood cells and the low price irregular antibody. In 570 cases (12.5%) of ineffective red blood cell infusion, 570 cases of ineffective red blood cell infusion (12.5%) were compared to male Chi 2=36.81, P0.01; the history of blood transfusion was compared with those without the history of blood transfusion, X 2=619.6, P0.01; the pregnancy history was compared with those without pregnancy history, and 2=85.5 was compared with those without pregnancy history, and 71 cases of P0.01. were ineffective because of low price irregular antibodies. Ineffective 12.4%. conclusion the inefficacy of erythrocyte infusion in Nanyang area is closely related to the leakage of low effective price irregular antibody. The low price irregular antibody is closely related to the history of blood transfusion, pregnancy, blood transfusion, and the number of pregnancy. The combination of the control reagent and the modified polyamine method combined with the antiglobulin method can improve the detection rate and avoid the ineffective infusion of the patients because of the low titer irregular antibody.
【作者单位】：南阳市中心血站;南阳市中心医院;
【分类号】：R457.1

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