广东省细菌耐药监测网2014年细菌耐药性监测

发布时间：2018-06-20 12:49

本文选题：细菌耐药性监测 + 耐药率　；参考：《中国抗生素杂志》2016年04期

【摘要】：目的分析广东省细菌耐药监测网2014年度细菌分布及耐药情况。方法采用标准纸片扩散法或自动化仪器检测法,测定监测药物对细菌敏感性,用WHONET 5.6软件进行数据分析。结果共有59家医院的171332株细菌药敏试验信息纳入研究,包括革兰阴性菌117538株(68.6%)和革兰阳性菌53794株(31.4%)。耐甲氧西林金黄色葡萄球菌(methicillin-resistant Staphylococcus aureus,MRSA)检出率为36.7%。万古霉素耐药粪肠球菌和屎肠球菌分别占0.3%和1.8%。青霉素耐药的肺炎链球菌比例为4.8%。革兰阴性菌中分离率前3位分别为大肠埃希菌(30.7%)、克雷伯菌属(16.8%)和铜绿假单胞菌(14.7%)。大肠埃希菌对头孢噻肟的耐药率为53.9%。肺炎克雷伯菌对亚胺培南耐药率为2.4%。铜绿假单胞菌对碳青酶烯类、氨基糖苷类、哌拉西林/三唑巴坦、头孢吡肟和头孢他啶的耐药率低于17.5%。鲍曼不动杆菌对大多数监测药物耐药率超过44.0%。广泛耐药肺炎克雷伯菌(extensively drug-resistant Klebsiella pneumoniae,XDRKP)和鲍曼不动杆菌(extensively drug-resistant Acinetobacter baumannii,XDRAB)比例分别为7.8%和22.1%。结论我省细菌耐药菌的构成比以及对常见抗菌药物耐药性与既往监测比较变化不大,鲍曼不动杆菌的耐药状况仍然最突出。
[Abstract]:Objective to analyze the distribution and drug resistance of bacteria in Guangdong Province in 2014. Methods the susceptibility of drug to bacteria was determined by standard disk diffusion method or automatic instrument, and the data were analyzed by WHONET 5.6 software. Results A total of 171332 strains of bacteria were tested in 59 hospitals, including 117538 Gram-negative bacteria (117538 strains) and 53794 Gram-positive bacteria (53794 strains). The detection rate of methicillin-resistant Staphylococcus aureus MRSAA was 36.7%. Vancomycin resistant Enterococcus faecalis and Enterococcus faecium accounted for 0.3% and 1.8% respectively. The proportion of penicillin resistant streptococcus pneumoniae was 4.8%. Among Gram-negative bacteria, the first three were Escherichia coli 30.7, Klebsiella 16.8) and Pseudomonas aeruginosa 14.775. The resistance rate of Escherichia coli to cefotaxime was 53.9%. The resistance rate of Klebsiella pneumoniae to imipenem was 2.4%. The resistance rate of Pseudomonas aeruginosa to carbocyanenes, aminoglycosides, piperacillin / triazobactam, cefepime and ceftazidime was lower than that of ceftazidime. Acinetobacter baumannii is more than 44. 0% resistant to most of the drugs monitored. The rates of extensible drug-resistant Klebsiella pneumoniae XDRKP and extensible drug-resistant Acinetobacter Baumannii XDRAB were 7.8% and 22.1%, respectively. Conclusion the composition ratio of bacteria resistant bacteria and drug resistance to common antimicrobial agents in our province have little change compared with previous monitoring. The drug resistance of Acinetobacter baumannii is still the most prominent.
【作者单位】：广州医科大学附属第一医院;
【分类号】：R446.5

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