成分单采技术在预存式自体输血中的应用研究

发布时间：2018-07-26 09:02

【摘要】：目的将成分单采技术用于预存式自体输血,评估其在成分式预存自体输血中的安全性、有效性。方法以普外科、骨科的择期手术患者中符合预存式自体输血指证患者109例为研究对象,分析比较术前采集自体全血、成分单采自体红细胞及未进行自体血预存的3组患者,术前、术后1 d、3 d Hb、Hct、Plt变化,及术后异体血输注率、术后平均住院日等指标,评价预存式自体成分输血的有效性。结果自体成分血组患者术后1 d、3 d Hb(117.66±18.02)g/L vs.(118.4±16.79)g/L vs.(143.6±10.96)g/L,P0.05;Hct(36.26±4.63)%vs.(36.24±4.85)%vs.(43.17±3.15)%,P0.05;Plt(201.29±58.09)×109/L vs.(202.28±48.06)×109/L vs.(240.11±72.29)×109/L,P0.05均较术前下降;与术前比较自体全血组患者术后1 d、3 d Hb(139.43±12.11)g/L vs.(114.93±15.87)g/L vs.(112.72±17.9)g/L,P0.05;Hct(42.45±3.08)%vs.(35.73±4.3)%vs.(34.08±5.44)%,P0.05;Plt(242.36±56.25)×109/L vs.(205.84±65.73)×109/L vs.(197.89±54.71)×109/L,P0.05均降低;对照组术后1 d、3 d较术前Hb(117.7±18.42)g/L vs.(112.62±18.2)g/L vs.(139.97±11.12)g/L,P0.05;Hct(35.33±5.26)%vs.(33.73±5.42)%vs.(42.33±3.86)%,P0.05;Plt(166.27±57.74)×109/L vs.(154.08±55.75)×109/L vs.(216.13±82.21)×109/L,P0.05均降低,但3组患者术后Hb110 g/L,Hct≥33%。3组患者术后1 d、3 d Hb、Hct变化差异无统计学意义(P0.05),自体成分血组及自体全血组术后1 d、3 d Plt高于对照组(P0.05)。自体成分血组与对照组比较有效缩短了术后平均住院日(17.93±7.13)d,(13.09±5.58)d,P0.05,与自体全血组比较差异无统计学意义(13.09±5.58)d,(14.39±5.13)d,P0.05。自体成分血组患者的异体血输注率与自体全血组比较差异无统计学意义(11.4%,22.7%,P0.05)。结论将成分单采技术用于自体成分血输注,有利于缩短平均住院时间,降低异体血输注率,此技术用于自体成分输血具有可行性,安全有效。
[Abstract]:Objective to evaluate the safety and effectiveness of single component autotransfusion in preexisting autologous blood transfusion. Methods 109 patients with preexisting autologous blood transfusion in general surgery and orthopedic department were studied. The autologous whole blood was collected before operation, autologous erythrocyte was collected alone and autologous blood was not pre-stored. Before and 1 day after operation, the changes of Hb HctTX Plt, the rate of allogeneic blood transfusion, and the average hospitalization days after operation were evaluated to evaluate the efficacy of pre-stored autogenous component transfusion. 缁撴灉鑷�浣撴垚鍒嗚。�

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