合肥地区HBsAg、梅毒抗体阳性献血者追踪情况分析

发布时间：2018-07-27 17:11

【摘要】：目的通过对阳性献血者的追踪检测,为建立献血者屏蔽和归队策略提供依据。方法对血筛HBs Ag、梅毒抗体ELISA及HBV NAT不合格献血者屏蔽8周后追踪采样,同时进行ELISA双试剂、NAT和相应补充、确证试验。结果共追踪到献血者61人。追踪检测结果:17名HBs Ag阳性献血者中,双试剂阳性8名:HBs Ag、NAT、抗-HBc和中和试验均阳性6人;HBs Ag、NAT和中和试验均阳性1人;HBs Ag和NAT阳性1人。单试剂阳性7名:HBs Ag和抗-HBc阳性2人;单独HBs Ag阳性5人。单试剂灰区2名:都是单独抗-HBc阳性。21名梅毒抗体阳性献血者中13人ELISA阳性,其中4人TPPA确证阳性,2人TPPA不确定;另外8人ELISA阴性。23名ELISA阴性NAT阳性献血者中,HBs Ag和NAT均阳性2人,单独NAT阳性6人,HBs Ag和NAT均阴性15人。结论针对不同情况的献血者应制定不同的屏蔽策略;同时可以通过对受屏蔽献血者的追踪检测,制定科学合理的归队策略。
[Abstract]:Objective to provide evidence for establishing screening and return strategy of blood donors by tracing and testing positive blood donors. Methods the blood sieve HBs Ag, syphilis antibody ELISA and HBV NAT unqualified blood donors were screened for 8 weeks, then the samples were followed up, and ELISA double reagents, Nat and corresponding supplementation were carried out to confirm the test. Results A total of 61 blood donors were found. The results were as follows: among 17 HBs Ag positive blood donors, 8 were positive for HBs Agnat, 6 were positive for anti-HBc and neutralization test, 1 was positive for HBs Ag and 1 for neutralization test. 7 cases were positive for HBs Ag and 2 cases were positive for anti-HBc, and 5 cases were positive for HBs Ag alone. In the single reagent gray area, 13 were ELISA positive, 4 were confirmed positive by TPPA, and 2 were TPPA, among the 21 blood donors who were positive for anti-HBc and 21 positive for syphilis antibody. In the other 8 ELISA negative, 23 ELISA negative NAT positive blood donors, both HBs Ag and NAT were positive in 2 cases, and NAT positive 6 cases were negative for HBs Ag and NAT in 15 cases. Conclusion different screening strategies should be made for blood donors under different conditions and a scientific and reasonable strategy for returning blood donors can be made by tracing and testing the blood donors.
【作者单位】：安徽省血液中心;中国医学科学院北京协和医学院输血研究所;
【基金】：2013年国家卫生和计划生育委员会委托项目
【分类号】：R457.1

【相似文献】