红细胞分布宽度对老年脓毒症患者预后评估的价值
发布时间:2018-08-11 21:40
【摘要】:目的探讨红细胞分布宽度(RDW)与老年脓毒症患者近期预后的关系。方法采用回顾性研究的方法,选取2013年8月至2014年11月上海市浦东新区周浦医院ICU收治的符合脓毒症诊断标准的老年患者204例,入院后收集患者一般资料,符合脓毒症诊断后12h内的降钙素原(PCT)、C反应蛋白(CRP)、血常规、D-二聚体、N氨基末端脑钠肽(NT-proBNP)指标,24h内最差指标进行急性生理与慢性健康评分系统Ⅱ(APACHEⅡ)。根据30d转归分为死亡组及存活组。比较两组间一般资料、各项检验指标及APACHEⅡ评分。使用Cox生存分析模型确定脓毒症预后的独立危险因素。建立受试者工作特征(ROC)曲线分析独立危险因素对脓毒症预后的预测价值。按照4分法分将RDW为Q1组(RDW12.24%)、Q2组(12.24%≤RDW13.27%)、Q3组(13.27%≤RDW14.30%)、Q4组(RDW≥14.30%),并绘制Kaplan-Meier生存曲线。结果(1)两组间的PCT、RDW、D-二聚体、NT-proBNP指标及APACHEⅡ评分差异有统计学意义(P0.05);(2)Cox生存分析结果显示,RDW及APACHEⅡ评分是脓毒症预后的独立危险因素(P0.01);(3)RDW及APACHEⅡ评分的曲线下面积相似分别为0.69、0.71,最佳截断值分别为14.18、19.50;(4)Kaplan-Meier生存曲线结果显示随着RDW指标升高,平均生存时间呈下降趋势(χ~2=22.84,P0.01)。结论 RDW水平与老年脓毒症患者疾病危重程度相关,是死亡的独立危险因素。
[Abstract]:Objective to investigate the relationship between erythrocyte distribution width (RDW) and short-term prognosis of senile sepsis. Methods from August 2013 to November 2014, 204 elderly patients with sepsis who were admitted to Zhoupu Hospital, Pudong New District, Shanghai from August 2013 to November 2014 were selected and the general data of the patients were collected. Calcitonin proto (PCT) C-reactive protein (CRP),) was the worst index of acute physiology and chronic health scoring system 鈪,
本文编号:2178311
[Abstract]:Objective to investigate the relationship between erythrocyte distribution width (RDW) and short-term prognosis of senile sepsis. Methods from August 2013 to November 2014, 204 elderly patients with sepsis who were admitted to Zhoupu Hospital, Pudong New District, Shanghai from August 2013 to November 2014 were selected and the general data of the patients were collected. Calcitonin proto (PCT) C-reactive protein (CRP),) was the worst index of acute physiology and chronic health scoring system 鈪,
本文编号:2178311
本文链接:https://www.wllwen.com/huliyixuelunwen/2178311.html
最近更新
教材专著