儿童卡他莫拉菌呼吸道感染的耐药性研究

发布时间：2018-10-21 09:46

【摘要】：目的探讨儿童呼吸道卡他莫拉菌的感染率与耐药性,为指导临床合理用药提供参考依据。方法选取2012年1月-2015年1月医院收治的1 240例呼吸道感染患儿,对其送检标本进行病原菌培养和药敏试验,采用K-B纸片法进行药敏试验,药敏结果按照美国临床实验室标准化研究所(CLSI)标准进行判定,采用SPSS20.0软件对数据进行统计分析。结果 1 240份标本共分离出138株卡他莫拉菌,检出率为11.13%,其中肺炎、哮喘并发感染、毛细支气管炎、支气管炎分别占66.67%、15.22%、10.14%和7.97%;卡他莫拉菌感染患儿性别比较差异无统计学意义,年龄分布和感染季节分布比较,差异有统计学意义(P0.05);卡他莫拉菌对阿莫西林/克拉维酸、环丙沙星、左氧氟沙星、克拉霉素、头孢哌酮/舒巴坦和亚胺培南敏感率均90.00%。结论儿童作为卡他莫拉菌感染的高危人群,尤其对于3岁以下和冬季患病儿童,应及时行药敏试验,合理选择抗菌药物治疗。
[Abstract]:Objective to investigate the infection rate and drug resistance of children with respiratory tract Morrah. Methods A total of 1,240 children with respiratory tract infection from January 2012 to January 2015 were selected for pathogen culture and drug sensitivity test, and K-B disk method was used for drug sensitivity test. The drug sensitivity results were determined according to the (CLSI) standard of American Institute of Clinical Laboratory Standardization, and the data were statistically analyzed by SPSS20.0 software. Results 138 strains of Mora carinii were isolated from 1 240 specimens, the positive rate was 11.13. Pneumonia, asthma complicated with infection, bronchitis and bronchitis accounted for 66.67% and 7.97%, respectively. There were significant differences between age distribution and seasonal distribution of infection (P0.05), and the susceptibility rates of the strains to amoxicillin / clavulanic acid, ciprofloxacin, levofloxacin, clarithromycin, cefoperazone / sulbactam and imipenem were all 90.00cm. Conclusion as a high risk group for the infection of Mora katamurium, especially for children under 3 years of age and children with disease in winter, the drug sensitivity test should be carried out in time and the antimicrobial therapy should be reasonably selected.
【作者单位】：湖北省监利县人民医院儿科;湖北省妇幼保健院儿童呼吸科;
【基金】：湖北省自然科学基金资助项目(2013CFC0098)
【分类号】：R446.5

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