谷氨酰胺对我国脓毒症患者疗效的meta分析
发布时间：2018-10-22 10:03
【摘要】：目的评价谷氨酰胺强化的营养支持对我国脓毒症患者疗效的影响,为临床治疗提供参考依据。方法系统检索国内外数据库,收集所有使用谷氨酰胺强化营养支持治疗脓毒症患者的随机对照试验,采用stata 11.0统计软件进行meta分析,并进行分层分析和灵敏度分析。结果共纳入22篇随机对照研究结果显示,与对照组比较,谷氨酰胺强化营养支持降低脓毒症患者的ICU住院天数、改善急性生理与APACHEⅡ评分、升高血清IgG水平、降低C-反应蛋白(CRP)水平,差异均有统计学意义(P0.05)。结论谷氨酰胺强化治疗能改善我国脓毒症患者临床结局、提高免疫功能及降低炎症反应,有利于预后。
[Abstract]:Objective to evaluate the effect of glutamine-enhanced nutritional support on the efficacy of sepsis in China and to provide reference for clinical treatment. Methods A systematic search of domestic and foreign databases was conducted to collect all randomized controlled trials of patients with sepsis treated with glutamine fortified nutrition support. Meta analysis was performed with stata 11.0 statistical software, and stratified analysis and sensitivity analysis were carried out. Results A total of 22 randomized controlled studies were conducted. Compared with the control group, intensive nutrition support with glutamine decreased the duration of ICU hospitalization, improved acute physiology and APACHE 鈪，
本文编号：2286859
[Abstract]:Objective to evaluate the effect of glutamine-enhanced nutritional support on the efficacy of sepsis in China and to provide reference for clinical treatment. Methods A systematic search of domestic and foreign databases was conducted to collect all randomized controlled trials of patients with sepsis treated with glutamine fortified nutrition support. Meta analysis was performed with stata 11.0 statistical software, and stratified analysis and sensitivity analysis were carried out. Results A total of 22 randomized controlled studies were conducted. Compared with the control group, intensive nutrition support with glutamine decreased the duration of ICU hospitalization, improved acute physiology and APACHE 鈪，
本文编号：2286859
本文链接：https://www.wllwen.com/huliyixuelunwen/2286859.html
最近更新
教材专著
