护理干预对老年痴呆患者生活质量影响的Meta分析

发布时间：2019-01-27 21:59

【摘要】：目的系统评价护理干预对老年痴呆患者生活质量的影响。方法计算机检索相关期刊论文、中国生物医学文献数据库、万方数据库、维普期刊资源整合服务平台、Cochrane图书馆、Medline、EMbase、EBSCO中关于护理干预对老年痴呆患者生活质量影响的随机对照试验,同时筛查纳入文献的参考文献。由2名研究者对文献质量进行严格评价和资料提取,对符合质量标准的研究进行Meta分析。结果共纳入12篇随机对照试验(RCT)研究,包括675例患者。Meta分析结果证实,护理干预能够:降低ADL评分,合并效应有统计学意义[MD=-2.32,95%CI为(-3.21,-1.43),Z=5.11,P0.001];提高老年痴呆患者的MMSE评分,合并效应有统计学意义[MD=2.55,95%CI为(1.34,3.76),Z=4.14,P0.001];降低HAMD评分,合并效应有统计学意义[MD=-4.59,95%CI为(-8.16,-1.03),Z=2.52,P=0.01];提高老年痴呆患者QOL-AD评分,合并效应有统计学意义[MD=2.49,95%CI为(1.00,3.97),Z=3.28,P=0.001]。结论护理干预在提高老年痴呆患者的日常生活能力、改善精神心理状况以及生活质量方面显示出积极的效果。
[Abstract]:Objective to evaluate the effect of nursing intervention on the quality of life of senile dementia patients. Methods the full text database of Chinese periodicals, the database of Chinese biomedical literature, the database of Wanfang, the service platform of WIP periodical resources integration, the Cochrane library, Medline,EMbase, A randomized controlled trial on the effect of nursing intervention on the quality of life of senile dementia patients in EBSCO. The quality of literature was evaluated and extracted by two researchers, and Meta analysis was carried out for the research in accordance with the quality standard. Results A total of 12 randomized controlled trial (RCT) studies, including 675 patients, were included. The results of Meta analysis confirmed that nursing intervention could reduce the ADL score, and the combined effect was statistically significant [MD=-2.32,95%CI = (-3.21), (-3.21), (-3.21), (-3.21), (-3.21) -1.43), Zang 5.11p 0.001]; Increasing the MMSE score of senile dementia patients, the combined effect was statistically significant [MD=2.55,95%CI = (1.34 卤3.76), Z _ (4.14) P _ (0.001)]; When the HAMD score was decreased, the combined effect was statistically significant [MD=-4.59,95%CI was (-8.16) -1.03, Z _ (2.52) P ~ (0. 01)]; There was statistical significance in increasing QOL-AD score of senile dementia patients [MD=2.49,95%CI = (1.00 卤3.97), Z _ (3.28) P ~ (0. 001)]. Conclusion Nursing intervention has a positive effect on improving the ability of daily life, improving mental and psychological status and quality of life of senile dementia patients.
【作者单位】：泰山医学院护理学院;
【分类号】：R473.74

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