人工髋关节置换术后患者感染病原菌分析

发布时间：2019-02-11 13:09

【摘要】：目的探讨人工髋关节置换术后手术部位早期感染的病原菌分布及相关危险因素,为降低人工髋关节置换术后感染提供参考依据。方法回顾性分析医院2010年4月-2015年3月1 010例行髋关节置换术患者的临床资料,分析术后手术部位早期感染病原菌分布特点,logistic回归分析感染相关危险因素,应用SPSS 15.0软件进行统计分析。结果 1 010例患者术后发生手术部位早期感染30例,感染率为2.97%,共检出病原菌19株,其中革兰阳性菌14株占73.68%,革兰阴性菌5株占26.32%;多因素logistic回归分析结果显示,高龄、手术持续时间长、引流时间长、低白蛋白水平、既往髋关节手术史、合并糖尿病是人工髋关节置换术后感染的独立危险因素(P0.05)。结论人工髋关节置换术后手术部位早期感染病原菌以革兰阳性菌为主,手术部位感染影响因素较多,临床上应采取相应的预防措施。
[Abstract]:Objective to investigate the pathogenic bacteria distribution and related risk factors of early infection after hip arthroplasty in order to provide reference for reducing infection after artificial hip arthroplasty. Methods the clinical data of 1,010 patients undergoing hip arthroplasty from April 2010 to March 2015 were retrospectively analyzed. The distribution of pathogens in early postoperative site infection and the risk factors of infection were analyzed by logistic regression analysis. SPSS 15.0 software was used for statistical analysis. Results among 1010 patients, early infection occurred in the surgical site in 30 cases, the infection rate was 2.97. A total of 19 strains of pathogenic bacteria were detected, of which 14 were Gram-positive bacteria (73.68) and 5 Gram-negative bacteria (26.32%). The results of multivariate logistic regression analysis showed that old age, long operation duration, long drainage time, low albumin level, previous hip surgery history and diabetes mellitus were independent risk factors for infection after artificial hip arthroplasty (P0.05). Conclusion Gram-positive bacteria are the main pathogens of early infection after artificial hip arthroplasty, and there are many factors affecting the infection in the operation site. The corresponding preventive measures should be taken in clinic.
【作者单位】：滨州市人民医院骨科二病区;滨州市人民医院耳鼻咽喉头颈外科;滨州市人民医院收发室;山东省邹平县中医院普外科;滨州医学院附属医院内镜室;
【基金】：国家自然科学基金资助项目(81271105)
【分类号】：R687.4;R446.5

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