NICU脑出血气管切开患者肺部感染病原菌分布与耐药性分析

发布时间：2019-02-20 07:46

【摘要】：目的分析神经外科重症监护病房(NICU)高血压脑出血气管切开患者肺部感染的病原菌分布及其耐药性,为临床合理选取抗菌药物预防和治疗肺部感染提供指导。方法收集2013年8月-2015年8月NICU收治的79例高血压脑出血气管切开患者的痰标本进行培养,分析病原菌及其耐药性。结果 79例患者送检痰标本共培养病原菌223株,其中革兰阴性菌167株占74.89%,以肺炎克雷伯菌为主占30.49%,其次为铜绿假单胞菌占17.94%;革兰阳性菌56株占25.11%,以金黄色葡萄球菌为主占15.25%;革兰阴性菌对头孢曲松、哌拉西林的耐药率均55.00%,革兰阳性菌对氨苄西林、夫西地酸、头孢唑林、苯唑西林的耐药率均97.00%。结论革兰阴性菌、革兰阳性菌分别是NICU高血压脑出血患者气管切开术后肺部感染常见的病原菌,且其耐药性强,临床应合理选择抗菌药物进行有效治疗。
[Abstract]:Objective to analyze the pathogenic bacteria distribution and drug resistance of pulmonary infection in patients with (NICU) hypertensive intracerebral hemorrhage tracheotomy in neurosurgery intensive care unit (ICU), and to provide guidance for the rational selection of antimicrobial agents for the prevention and treatment of pulmonary infection. Methods the sputum samples of 79 patients with hypertensive intracerebral hemorrhage treated by tracheotomy from August 2013 to August 2015 were collected and the pathogens and their drug resistance were analyzed. Results 223 strains of pathogenic bacteria were cultured in sputum samples of 79 patients, of which 167 were Gram-negative bacteria (74.89), mainly Klebsiella pneumoniae (30.49), followed by Pseudomonas aeruginosa (17.94). There were 56 Gram-positive bacteria (25.11%) and Staphylococcus aureus (15.25%). The resistance rates of Gram-negative bacteria to ceftriaxone and piperacillin were 55.00, and the resistance rates of Gram-positive bacteria to ampicillin, fossillic acid, cefazolin and oxacillin were 97.00. Conclusion Gram-negative bacteria and Gram-positive bacteria are common pathogens of pulmonary infection after tracheotomy in patients with NICU hypertensive intracerebral hemorrhage.
【作者单位】：安阳市人民医院神经外科;安阳市汤阴县人民医院重症医学科;
【基金】：河南省科技厅重点基金资助项目(20140210)
【分类号】：R446.5

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