阴道模具在预防青年宫颈癌患者放疗后阴道狭窄的效果研究
发布时间：2019-06-05 05:21
【摘要】：目的：(1)探讨青年宫颈癌放疗后患者使用阴道模具预防阴道狭窄的临床效果。(2)探讨青年宫颈癌放疗后患者使用阴道模具对患者性生活质量的影响。(3)探讨青年宫颈癌放疗后患者使用阴道模具预防阴道狭窄的安全性和可行性。方法：选择2014年1月～2014年6月在浙江省肿瘤医院妇瘤科行放射治疗的青年官颈癌患者为研究人群,根据纳入、排除标准选取110例患者,随机分为观察组55例,对照组55例。对照组患者行常规护理,放疗期间每日由护士进行阴道冲洗,出院以后要求患者自行阴道冲洗,每日一次,持续一年,放疗结束3个月后恢复性生活。观察组患者在常规护理的基础上,于放疗结束时指导患者居家阶段采用专用的阴道模具每周进行大于等于3次阴道扩张,每次扩张持续5分钟,持续1年以上。比较观察组和对照组患者阴道狭窄发生率、阴道狭窄程度、性生活恢复情况以及女性性功能量表(FSFI)分值差异。结果：项目实施过程中,本研究共募集组观察组55人,对照组55人,观察组脱落6人,对照组脱落5人,最终纳入统计分析的青年宫颈癌患者总数为99例,观察组49例,对照组50例。观察组患者阴道狭窄的发生率为22.45%,均为Ⅰ级阴道狭窄,对照组患者阴道狭窄的发生率为60.00%,其中Ⅰ级阴道狭窄为30.00%，Ⅱ级阴道狭窄为30.00%,差异有统计学差异(P0.05)。至放疗结束后12个月,观察组患者性生活恢复率为81.64%,对照组为54.00%,差异有统计学意义(P0.05)。观察组患者恢复性生活的时间为放疗结束后9.24±2.57个月,对照组患者恢复性生活的时间为放疗结束后9.78±3.11个月,两组比较无显著性差异(P0.05)。观察组患者每月性生活次数3.00±1.90次,对照组患者每月性生活次数1.62±1.87次,两组比较存在显著差异(P0.05)。观察组FSFI问卷总分18.163±8.795分,对照组总分12.740±8.389分,两组比较存在显著性差异(P0.05)。模具使用过程中无1例发生模具相关的并发症。结论：(1)青年宫颈癌患者放疗后使用阴道模具能有效降低阴道狭窄的发生率；(2)青年官颈癌患者放疗后使用阴道模具能促进患者恢复性生活,提高性生活质量；(3)青年宫颈癌放疗后患者使用阴道模具预防阴道狭窄是安全、可行的。
[Abstract]:Objective: (1) to investigate the clinical effect of vaginal mould on prevention of vaginal stricture in young patients with cervical cancer after radiotherapy. (2) to investigate the effect of vaginal mould on sexual life quality of young patients with cervical cancer after radiotherapy. (2) to investigate the effect of vaginal mould on sexual life quality of young patients with cervical cancer after radiotherapy. 3) to investigate the safety and feasibility of using vaginal mould to prevent vaginal stricture in young patients with cervical cancer after radiotherapy. Methods: from January 2014 to June 2014, 110 young patients with cervical cancer who underwent radiotherapy in the Department of Gynecology, Zhejiang Cancer Hospital were randomly divided into observation group (n = 55) and control group (n = 55). The patients in the control group were treated with routine nursing. During radiotherapy, the nurses were washed with vagina every day. After discharge, the patients were asked to rinse their own vagina once a day for one year. After 3 months of radiotherapy, the patients were asked to resume their sex life. On the basis of routine nursing, the patients in the observation group were given vaginal dilatation more than or equal to 3 times a week at the end of radiotherapy. Each dilatation lasted for 5 minutes and lasted for more than 1 year. The incidence of vaginal stricture, the degree of vaginal stricture, the recovery of sexual life and the (FSFI) score of female sexual function scale were compared between the observation group and the control group. Results: during the implementation of the project, there were 55 cases in the observation group, 55 cases in the control group, 6 cases in the observation group and 5 cases in the control group. The total number of young cervical cancer patients included in the statistical analysis was 99 cases and 49 cases in the observation group. There were 50 cases in the control group. The incidence of vaginal stricture was 22.45% in the observation group and 60.00% in the control group, including 30.00% in grade I vaginal stenosis and 30.00% in grade II vaginal stenosis. The difference was statistically significant (P 0.05). 12 months after radiotherapy, the sexual recovery rate of the observation group was 81.64%, and that of the control group was 54.00%, the difference was statistically significant (P 0.05). The time of resuming sexual life was 9.24 卤2.57 months after radiotherapy in the observation group and 9.78 卤3.11 months after radiotherapy in the control group. There was no significant difference between the two groups (P 0.05). The monthly sexual life times of the patients in the observation group were 3.00 卤1.90 times, while those in the control group were 1.62 卤1.87 times per month. There was a significant difference between the two groups (P 0.05). The total score of FSFI questionnaire was 18.163 卤8.795 in the observation group and 12.740 卤8.389 in the control group. There was significant difference between the two groups (P 0.05). No complications related to mould occurred in the process of mould use. Conclusion: (1) vaginal mould can effectively reduce the incidence of vaginal stricture in young patients with cervical cancer after radiotherapy, (2) vaginal mould can promote the recovery of sexual life and improve the quality of sexual life in young patients with cervical cancer after radiotherapy. (3) it is safe and feasible for young patients with cervical cancer to use vaginal mould to prevent vaginal stenosis after radiotherapy.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R473.73
本文编号：2493288
[Abstract]:Objective: (1) to investigate the clinical effect of vaginal mould on prevention of vaginal stricture in young patients with cervical cancer after radiotherapy. (2) to investigate the effect of vaginal mould on sexual life quality of young patients with cervical cancer after radiotherapy. (2) to investigate the effect of vaginal mould on sexual life quality of young patients with cervical cancer after radiotherapy. 3) to investigate the safety and feasibility of using vaginal mould to prevent vaginal stricture in young patients with cervical cancer after radiotherapy. Methods: from January 2014 to June 2014, 110 young patients with cervical cancer who underwent radiotherapy in the Department of Gynecology, Zhejiang Cancer Hospital were randomly divided into observation group (n = 55) and control group (n = 55). The patients in the control group were treated with routine nursing. During radiotherapy, the nurses were washed with vagina every day. After discharge, the patients were asked to rinse their own vagina once a day for one year. After 3 months of radiotherapy, the patients were asked to resume their sex life. On the basis of routine nursing, the patients in the observation group were given vaginal dilatation more than or equal to 3 times a week at the end of radiotherapy. Each dilatation lasted for 5 minutes and lasted for more than 1 year. The incidence of vaginal stricture, the degree of vaginal stricture, the recovery of sexual life and the (FSFI) score of female sexual function scale were compared between the observation group and the control group. Results: during the implementation of the project, there were 55 cases in the observation group, 55 cases in the control group, 6 cases in the observation group and 5 cases in the control group. The total number of young cervical cancer patients included in the statistical analysis was 99 cases and 49 cases in the observation group. There were 50 cases in the control group. The incidence of vaginal stricture was 22.45% in the observation group and 60.00% in the control group, including 30.00% in grade I vaginal stenosis and 30.00% in grade II vaginal stenosis. The difference was statistically significant (P 0.05). 12 months after radiotherapy, the sexual recovery rate of the observation group was 81.64%, and that of the control group was 54.00%, the difference was statistically significant (P 0.05). The time of resuming sexual life was 9.24 卤2.57 months after radiotherapy in the observation group and 9.78 卤3.11 months after radiotherapy in the control group. There was no significant difference between the two groups (P 0.05). The monthly sexual life times of the patients in the observation group were 3.00 卤1.90 times, while those in the control group were 1.62 卤1.87 times per month. There was a significant difference between the two groups (P 0.05). The total score of FSFI questionnaire was 18.163 卤8.795 in the observation group and 12.740 卤8.389 in the control group. There was significant difference between the two groups (P 0.05). No complications related to mould occurred in the process of mould use. Conclusion: (1) vaginal mould can effectively reduce the incidence of vaginal stricture in young patients with cervical cancer after radiotherapy, (2) vaginal mould can promote the recovery of sexual life and improve the quality of sexual life in young patients with cervical cancer after radiotherapy. (3) it is safe and feasible for young patients with cervical cancer to use vaginal mould to prevent vaginal stenosis after radiotherapy.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R473.73
【参考文献】
相关期刊论文 前1条
1 葛永勤;徐丽丽;李雪芬;刘宁;刘敏;于巧萍;;专项化护理干预对育龄期宫颈癌病人术后性生活质量的影响[J];护理研究;2014年20期
，本文编号：2493288
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