手性聚合物的合成及与金纳米粒子的组装

发布时间：2018-02-16 21:24

本文关键词： 手性螺旋分子 π共轭偶氮类聚合物圆二色谱金纳米粒子的手性组装　出处：《吉林大学》2017年硕士论文　论文类型：学位论文

【摘要】：手性作为生命体的基本特征之一在自然界是广泛存在的。从小分子如L-氨基酸、D-糖等到宏观尺寸如植物藤曼或者人体等都是手性存在方式。研究手性结构对我们探索生命的奥秘有着极其重要的作用,更是生命科学与化学学科连接的重要桥梁。受到天然手性分子的启发,通过合理的设计分子结构可以人工合成具有单一手性的分子,并且通过外界条件诱导也可使结构规整的聚合物具有手性结构和形貌。对于人造手性分子的研究俨然已经成为热门研究领域。并且近年来人们将手性分子与具有局域表面等离子体光学特性的金属纳米粒子相结合,得到了具有手性局域表面等离子体的金属纳米粒子复合材料,这对研究手性分子的特殊光学性质和材料的应用都做出了基础性贡献。本文从此立意出发,对手性螺旋分子和可与手性溶剂相互作用的π共轭聚合物进行了设计合成,并初步研究了π共轭聚合物在金纳米粒子表面的配体置换过程。1.设计合成了以吡啶为单体的螺旋三聚体和以吡啶、喹啉为单体的混合螺旋分子。通过多种方法对两种刚性芳香螺旋分子的结构进行了表征,确定其螺旋构型。在后者螺旋结构侧链中,引入单手性天然小分子半胱氨酸,由圆二色谱可证实得到了单一手性的螺旋结构,实现在柔性侧链末端对螺旋分子手性的远程调控。2.以RAFT聚合方法合成可与手性溶剂分子相互作用的π共轭偶氮类嵌段共聚物PAzoMA-b-MMA。探究其在不同溶剂中和手性溶剂相互作用从而实现手性表达的条件。明晰了PMMA嵌段对手性表达的作用。进一步利用嵌段共聚物中硫醇末端基与金晶面的强相互作用,实现了在金纳米棒上的表面接枝,并探究通过手性溶剂诱导金纳米粒子实现手性组装的条件。
[Abstract]:As one of the basic characteristics of chiral life in nature is widespread. Small molecules such as amino acids L-, D- sugar when the macro size such as plant vines or human body are chiral existence. It plays an important role on the mystery of chiral structure for us to explore life, is an important bridge of life science and chemistry connection. Inspired by the natural chiral molecules, molecules can be synthesized with chiral molecular structure through the design of reasonable, and the external conditions can also be induced by regular structure polymers with chiral structure and morphology. For the study of artificial chiral molecules has become a hot research field in recent years. And the people of chiral molecules and metal nanoparticles with localized surface plasmon optical properties has been combined with chiral localized surface plasmon metal The application of nanoparticles composite materials, this research of chiral molecules with special optical properties and materials has made fundamental contributions. This conception of chiral helical molecular and conjugated polymers and chiral solvent interactions were designed and synthesized, and the preliminary research of the conjugated polymers in the design of the ligand exchange process of.1. gold the surface of nanoparticles was synthesized with pyridine as helical trimer monomer and pyridine, quinoline mixed monomer. The spiral structure through a variety of methods on two kinds of rigid aromatic helical molecules were characterized to determine its helical configuration. In the latter spiral structure in the side chain, the introduction of a single natural chiral small molecules of cysteine two, the circular chromatography proved that the chiral helical structure, in the end of the spiral flexible side chain molecular chirality remote control.2. by RAFT polymerization synthesis The interaction with the chiral solvent n-conjugated azo triblock copolymer PAzoMA-b-MMA. in different solvents and explore the chiral solvent interaction conditions in order to achieve chiral expression. Clear expression of opponents of the PMMA block. The further use of block copolymers with thiol end groups and gold crystal face of strong interaction, realized surface grafting in the gold nanorods, and explore the implementation of gold nanoparticles induced by chiral assembly by chiral solvent conditions.

【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：O631.1;TB383.1

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