明胶基纳米复合材料的制备、表征及其应用

发布时间：2018-03-01 03:27

本文关键词： 明胶流变明胶/功能化石墨烯磁性明胶吸附　出处：《齐鲁工业大学》2015年硕士论文　论文类型：学位论文

【摘要】：明胶是一种可降解的生物高分子,价格便宜,来源丰富,无毒,生物相容性好,广泛的应用于食品、生物与医药等领域。本文系统地研究了明胶的粘度行为,以及明胶／纤维素的流变性能；制备了明胶功能化石墨烯、明胶／功能化石墨烯与磁性明胶,并探讨了其在药物输送和重金属离子吸附方面的应用。本文的主要研究内容如下：1、研究了不同浓度不同价态盐溶液中明胶的粘度行为,结果发现,氯化钠的加入使聚合物溶液的临界浓度C*(接触浓度)和Ce(缠结浓度)分别由原来的4Wt%和14Wt%(无盐条件下)降低到2Wt%和12Wt%。盐的加入提高了聚合物溶液的粘度,其中CaCl2比NaCl的影响更显著。2、通过明胶的生物还原性,成功的制备了明胶功能化的石墨烯。结果表明,明胶功能化的石墨烯具有优异的水溶性、较大的比表面积、较高的负载药物能力和药物释放时对pH值的依赖性。3、将制备的明胶功能化石墨烯与明胶共混制备了明胶／功能化石墨烯复合膜。明胶功能化的石墨烯能够很好的分散在明胶溶液中,并起到交联点的作用。研究发现,明胶／功能化石墨烯复合膜的溶胀性能下降,湿稳定性得到了改善,玻璃化转变温度有所提高。4、借助铁离子和明胶的静电相互作用,成功的将铁离子负载在明胶上。在弱碱性环境下,铁离子在明胶的网络结构中形成了四氧化三铁磁性粒子。结果表明,制备的磁性明胶具有很好的铬离子吸附性,并对其吸附机理和吸附动力学模型等进行了研究。5、通过水解法制备了纳米纤维素晶,考察了纳米纤维素晶及明胶／纳米纤维素晶悬浮液的流变性能。结果发现,纤维素晶悬浮液的粘度随浓度的增大而上升,模量随温度的升高而减小,且遵循时温等效叠加原理。明胶／纤维素晶悬浮液的粘度随着纤维素晶含量的增大而逐渐减小。
[Abstract]:Gelatin is a biodegradable polymer with low price, abundant sources, nontoxic, good biocompatibility, and widely used in food, biology and medicine. The viscosity behavior of gelatin has been studied systematically in this paper. The rheological properties of gelatin / cellulose, the preparation of gelatin functionalized graphene, gelatin / functionalized graphene and magnetic gelatin, The main contents of this paper are as follows: 1. The viscosity behavior of gelatin in different concentration and different valence salt solution is studied. The addition of sodium chloride reduced the critical concentration of polymer solution Con (contact concentration) and ce (entangled concentration) from 4Wt% and 14Wtb (without salt) to 2Wt% and 12Wt.The addition of salt increased the viscosity of polymer solution. The effect of CaCl2 was more significant than that of NaCl. The gelatin functionalized graphene was successfully prepared by the biological reduction of gelatin. The results showed that the gelatin functionalized graphene had excellent water solubility and large specific surface area. The higher drug loading capacity and the dependence of drug release on pH value. 3. The gelatin / functionalized graphene composite membrane was prepared by blending the prepared gelatin functionalized graphene with gelatin. The gelatin functionalized graphene can be very good. Dispersed in gelatin solution, It was found that the swelling property of gelatin / functionalized graphene composite membrane was decreased, the wet stability was improved, the glass transition temperature was increased by .4, and the electrostatic interaction of iron ion and gelatin was used. Iron ions were successfully loaded on gelatin. In weak alkaline environment, ferromagnetic particles were formed in the gelatin network structure. The results show that the magnetic gelatin prepared has good adsorption of chromium ion. The adsorption mechanism and adsorption kinetic model of nanocellulose were studied. 5. Nanocellulose crystals were prepared by hydrolysis method. The rheological properties of nanocellulose crystals and gelatin / nanocellulose suspensions were investigated. The viscosity of cellulose crystal suspension increases with the increase of concentration, and the modulus decreases with the increase of temperature, and follows the principle of equivalent superposition of time temperature. The viscosity of gelatin / cellulose crystal suspension decreases with the increase of cellulose crystal content.
【学位授予单位】：齐鲁工业大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：TB33

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