金纳米棒包覆钨酸钠钇粉体的制备及光热诊疗性能研究

发布时间：2018-06-20 05:46

本文选题：金纳米棒 + 钨酸钠钇　；参考：《中国钨业》2017年04期

【摘要】：为了扩展低长径比金纳米棒在信息、生物及医学等领域的应用范围,通过水热合成法掺杂稀土元素在金纳米棒表面包覆钨酸钠钇,制备出了荧光GNRs@NaY(WO_4)_2粉体。其相组成、显微组织形貌、发光性能、光热能力分别通过X射线衍射仪(XRD)、透射电镜(TEM)、荧光光谱仪(PL)和光热成像仪(PTI)进行检测。结果表明:荧光GNRs@NaY(WO_4)_2粉体的相组成、尺寸及形貌均匀一致;在980 nm激光激发下,Yb~(3+)/Er~(3+)共掺杂使样品呈现很强的绿光(~4S_(3/2),~2H_(11/2)→~4I_(15/2))和红光(~4F_(9/2)→~4I_(15/2));由于荧光共振能量迁移(FRET)机制影响,样品在红光区的发射强度下降,但其表面温度随时间的延长不断增加;与此同时,该粉体具有良好的生物相容性、低溶血性和一定的抗癌能力。
[Abstract]:In order to expand the application of gold nanorods with low aspect ratio in the fields of information, biology and medicine, the nanorods were coated with sodium yttrium tungstate by hydrothermal synthesis method. The phase composition, microstructure, luminescence properties and photothermal properties were measured by X-ray diffractometer (XRD), transmission electron microscopy (TEM), fluorescence spectrometer (PL) and photothermal imaging (PTI), respectively. The results show that the phase composition, size and morphology of the fluorescent GNRsR NaYR ^ NaYR / WO _ 4 / T _ 2 powder are uniform, and the co-doping of the Yb ~ (3 / er) ~ (3 / er ~ (3) doped with a 980nm laser makes the samples present a very strong green light (3 / 2 / 2 / 2 / 11 / 2) and the red light ~ (4 / 9 / 2); because of the mechanism of fluorescence resonance energy migration / FRET, The emission intensity of the sample decreases in the red region, but the surface temperature increases with time. At the same time, the powder has good biocompatibility, low hemolysis and certain anticancer ability.
【作者单位】：吉林化工学院材料科学与工程学院;郑州大学材料科学与工程学院;
【基金】：吉林省科技发展计划项目(20130102005JC) 吉林市科技创新发展计划项目(20161205)
【分类号】：TB383.1;TQ422

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