不同维数纳米材料的可控制备及其在电化学生物传感器中的应用
发布时间：2019-05-16 02:36
【摘要】：石墨烯和导电聚合物纳米材料具有导电性高,比表面积大、制备成本低廉和生物相容性良好等优点,在传感,能源贮存和电子器件等领域有着广泛应用。本论文分别采用模板法、水热法和化学气相沉积法(CVD)制备了一维的聚苯胺纳米管和聚苯胺/金复合纳米管,二维的二氧化锰/石墨烯复合物及具有三维网络结构的氮掺杂石墨烯纳米材料。通过透射电子显微镜(TEM)、扫描电子显微镜(SEM)、X射线光电子能谱(XPS)、粉末X射线衍射(XRD)、热重分析(TGA)、红外光谱(FTIR)、紫外-可见光谱(US-vis)和拉曼光谱(Raman)等测试对产品的结构、形貌及成分进行了表征,并对所制备在电化学生物传感器中的应用进行了研究。研究工作概述如下:1.以MnO2为反应性模板成功制备了具有良好电化学活性和一维结构的聚苯胺(PANI)纳米管,并将其用于生物传感器的电极材料。实验结果显示,所制备的PANI纳米管,管长和直径尺寸均匀,具有良好的管状结构。由PANI纳米管修饰的玻碳电极(GCE)在近中性的环境中对多巴胺(DA)的电化学氧化过程有良好的催化活性。差分脉冲测试的实验结果显示,该DA传感器对尿酸(UA),抗坏血酸(AA),葡萄糖(GC)有良好的抗干扰性。此外,该传感器呈现了两段线性检测范围分别为7×10-5-3×10-4和3×10-4-5×10-3 M,和一个较低的检测极限0.5×10-9M。2.制备了一维的聚苯胺/金(PANI/Au)复合纳米管,并将其用于检测还原型辅酶Ⅰ(nicotinamide adenine dinucleotide,NADH)。循环伏安(CV)测试结果显示在中性环境中该材料修饰的玻碳电极(GCE)对NADH的电化学氧化过程有很好的催化作用。差分脉冲(DPV)测试结果显示,该NADH传感器有良好的抗干扰性,并呈现出4×10-4-8×10-3 M的线性检测范围和0.5×10-7 M的检测极限。3.合成了不同形貌的二维二氧化锰/石墨烯(MnO2/graphene)纳米复合材料,并将花瓣状MnO 2纳米片/graphene复合材料用做过氧化氢(H2O2)非酶电化学检测的电极材料。循环伏安(CV)测试表明MnO2/graphene修饰的电极在中性环境中对H2O2的氧化和还原均有良好的电催化活性。恒电位检测结果显示所制备的非酶传感器有良好的抗干扰性,并呈现出两段线性检测范围分别为10-90μM和0.2-0.9 mM及2μM的检测极限。4.以多孔泡沫镍为模板,化学气相沉积法(CVD)成功制备三维氮掺杂石墨烯(3D-N-Graphene)材料。以此材料为例,构建了一个基于三维氮掺杂石墨烯泡沫的生物传感器,并将其用于多巴胺(DA)的检测。电化学测试表明该生物传感器对多巴胺有显著的检测效果,呈现出较宽的检测范围:3×10-6-1×10-4 M和较低的检测极限1 nM。此外,所制备的生物传感器亦表现出良好的抗干扰性、重复性和稳定性。
[Abstract]:Graphene and conductive polymer nanomaterials have many advantages, such as high conductivity, large specific surface area, low preparation cost and good biocompatibility. Graphene and conductive polymer nanomaterials are widely used in sensing, energy storage and electronic devices. In this paper, one-dimensional Polyaniline nanotubes and Polyaniline / gold composite nanotubes were prepared by template method, hydrothermal method and chemical vapor deposition (CVD), respectively. Two-dimensional manganese dioxide / graphene composites and nitrogen-doped graphene nanomaterials with three-dimensional network structure. Transmission electron microscope (TEM), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), powder X-ray diffraction (XRD), thermogravimetric analysis of (TGA), infrared spectrum (FTIR), The structure, morphology and composition of the product were characterized by UV-vis spectroscopy (US-vis) and Raman spectroscopy (Raman), and the application of the product in electrochemical biosensor was studied. The research work is summarized as follows: 1. Polyaniline (PANI) nanotubes with good electrochemical activity and one-dimensional structure were successfully prepared by using MnO2 as reactive template and used as electrode materials for biosensors. The experimental results show that the prepared PANI nanotube has uniform length and diameter, and has good tubular structure. The glassy carbon electrode (GCE) modified by PANI nanotube has good catalytic activity for the electrochemical oxidation of dopamine (DA) in a near-neutral environment. The experimental results of differential pulse test show that the DA sensor has good anti-interference effect on uric acid (UA), ascorbic acid (AA), glucose (GC). In addition, the sensor presents a linear detection range of 7 脳 10 鈮，
本文编号：2477953
[Abstract]:Graphene and conductive polymer nanomaterials have many advantages, such as high conductivity, large specific surface area, low preparation cost and good biocompatibility. Graphene and conductive polymer nanomaterials are widely used in sensing, energy storage and electronic devices. In this paper, one-dimensional Polyaniline nanotubes and Polyaniline / gold composite nanotubes were prepared by template method, hydrothermal method and chemical vapor deposition (CVD), respectively. Two-dimensional manganese dioxide / graphene composites and nitrogen-doped graphene nanomaterials with three-dimensional network structure. Transmission electron microscope (TEM), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), powder X-ray diffraction (XRD), thermogravimetric analysis of (TGA), infrared spectrum (FTIR), The structure, morphology and composition of the product were characterized by UV-vis spectroscopy (US-vis) and Raman spectroscopy (Raman), and the application of the product in electrochemical biosensor was studied. The research work is summarized as follows: 1. Polyaniline (PANI) nanotubes with good electrochemical activity and one-dimensional structure were successfully prepared by using MnO2 as reactive template and used as electrode materials for biosensors. The experimental results show that the prepared PANI nanotube has uniform length and diameter, and has good tubular structure. The glassy carbon electrode (GCE) modified by PANI nanotube has good catalytic activity for the electrochemical oxidation of dopamine (DA) in a near-neutral environment. The experimental results of differential pulse test show that the DA sensor has good anti-interference effect on uric acid (UA), ascorbic acid (AA), glucose (GC). In addition, the sensor presents a linear detection range of 7 脳 10 鈮，
本文编号：2477953
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