氧化锌纳米粒的制备与表征（英文）

发布时间：2021-06-21 06:21

　　本研究采用溶胶-凝胶法制备氧化锌纳米粒（ZnO NPs）,并对其粒径、形貌、晶型、光学特性和pH敏感性等理化性质进行表征,在PC-3M和4T1两株细胞系上对ZnO NPs的体外抗肿瘤药效进行评价。实验结果表明,ZnO NPs为粒径均匀的球形纳米颗粒,具有优良的光学性能及pH敏感性能,对PC-3M和4T1两株细胞系有明显的抗肿瘤细胞药效。上述结果表明, ZnO NPs可作为载体载带活性物质以产生抗肿瘤诊断和治疗作用。 

【文章来源】：Journal of Chinese Pharmaceutical Sciences. 2020,29(09)CSCD

【文章页数】：9 页

【文章目录】：
1. Introduction
2. Materials and methods
    2.1. Materials
    2.2. Cells
    2.3. Preparation of Zn O NPs
    2.4. Size distribution and morphology
    2.5. X-ray powder diffraction
    2.6. UV-Vis spectrum
    2.7. Fluorescence spectrum
    2.8. Fourier transform infrared spectrum
    2.9. p H-Responsive behavior
    2.1 0. In vitro anti-tumor activity
3. Results and discussion
    3.1. Preparation of Zn O NPs
    3.2. Size distribution and morphology
    3.3. X-ray powder diffraction
    3.4. UV-Vis spectrum
    3.5. Fluorescence spectrum
    3.6. FTIR spectrum
    3.7. p H-Responsive behavior
    3.8. In vitro anti-tumor activity
4. Conclusions


【参考文献】：
期刊论文
[1]包载共轭亚油酸-紫杉醇的iRGD修饰的含溶血磷脂的温敏脂质体的细胞摄取和抗肿瘤药效（英文）[J]. 郝艳丽,钟婷,杜若,张华,刘碧林,张烜.  Journal of Chinese Pharmaceutical Sciences. 2019(02)



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