三苯胺功能染料的合成及在谷胱甘肽超低电位光电检测中的应用

发布时间：2018-01-30 01:58

本文关键词： 光电传感器谷胱甘肽三苯胺光电功能材料超低电位检测　出处：《高等学校化学学报》2016年04期 　论文类型：期刊论文

【摘要】：设计合成了一种具有D-π-A结构的三苯胺功能染料(TCA),并通过分子结构中的羧基将其配位于TiO_2纳米粒子修饰的光电极表面,发展了一种可在超低电位下高灵敏检测谷胱甘肽(GSH)的光电传感方法.该TCA分子以三苯胺为电子给体,噻吩为桥连基团,氰基乙酸为电子受体.在可见光的照射下,TCA通过分子内电子转移将光电子由三苯胺经噻吩和羧基注入到TiO_2的导带能级,进而注入基底光电极,产生阳极光电流;同时,TCA被氧化到氧化态.由于氧化态TCA的稳定性好,可循环被生理活性小分子GSH还原,并产生放大的阳极光电流.TCA功能化的TiO_2纳米粒子修饰电极对GSH表现出了极高的催化活性,在波长为480 nm的可见光照射下,在0 V的超低电位下即可实现对GSH的催化氧化.基于这一性质,发展了一种可用于GSH检测的光电传感方法.在最优条件下,该传感器对浓度为2~100μmol/L和0.1~2.4 mmol/L的GSH具有良好的线性响应,检出限低达1μmol/L.此外,该光电传感器具有较好的选择性,可排除13种氨基酸和生理活性物质多巴胺及氢醌的干扰,因此具有一定的实际应用前景.
[Abstract]:A three D- -A with aniline dye PI structure was designed and synthesized (TCA), and its distribution in photoelectric TiO_2 nanoparticles modified electrode surface through the carboxyl groups in the molecular structure, has a low potential in the ultra high sensitive detection of glutathione (GSH) of the photoelectric sensor. The method of TCA molecule three aniline as electron donor, thiophene as a bridging group, cyanoacetic acid as electron acceptor. In the visible light irradiation, TCA through intramolecular electron transfer to photoelectron consists of three aniline by thiophene and injected into the conduction band of TiO_2 carboxyl groups, and then injected into the basal light electrode, produced anodic photocurrent; at the same time, the oxidation of TCA to the oxidation state. Because the stability of oxidized TCA, circulating was physiological activity of small molecule GSH reduction, and produce amplified anodic photocurrent of.TCA functionalized TiO_2 nanoparticles modified electrode of GSH exhibited very high catalytic activity in the wave, As long as the visible light irradiation of 480 nm, in the ultra low potential of 0 V can be achieved under the catalytic oxidation of GSH. Based on this characteristic, the development of a photoelectric sensor can be used for GSH detection method. Under the optimal conditions, the sensor to the concentration of 2~100 mol/L and 0.1~2.4 mmol/L with GSH good linear response, low detection limit of 1 mol/L. in addition, the photoelectric sensor has good selectivity, eliminating the interference of 13 kinds of amino acids and physiological activity of dopamine and hydroquinone, so it has certain application prospects.

【作者单位】：大连理工大学化学学院;
【基金】：国家自然科学基金(批准号:21275024) 辽宁省自然科学基金(批准号:2014020016) 中央高校基本科研业务费(批准号:DUT15LK33)资助~~
【分类号】：O657.1
【正文快照】： 光电传感技术是分析化学领域一门新兴的可用于生物分析的检测技术,它利用光电功能材料的特性,将光能转化成电能输出,并根据电信号的变化对被分析组分进行定量测定[1,2].光电传感技术将光激发与电检测有机地结合在一起,与单纯的光分析方法和电分析方法相比,该方法由于可将激发

【相似文献】