基于离子液体辅助氯霉素分子印迹聚合物的制备及应用

发布时间：2018-02-25 00:12

本文关键词： 氯霉素分子印迹聚合物离子液体鸡蛋样品分离富集　出处：《分析测试学报》2017年01期 　论文类型：期刊论文

【摘要】：以氯霉素(CAP)为模板,2-乙烯基吡啶(2-Vp)为功能单体,四氢呋喃和离子液体1-丁基-3-甲基咪唑四氟硼酸盐[BMIm]BF4的混合溶液为反应溶剂,乙二醇二甲基丙烯酸酯(EGDMA)为交联剂,偶氮二异丁腈(AIBN)为引发剂,合成了氯霉素的分子印迹及非印迹聚合物。优化功能单体、不同溶剂对印迹聚合物吸附性能的影响,结果表明,以2-乙烯基吡啶为功能单体,四氢呋喃和离子液体[BMIm]BF4(体积比1∶1)作为反应溶剂合成的分子印迹聚合物对氯霉素具有高的吸附容量,良好的特异性识别性能。氯霉素分子印迹聚合物的印迹因子为2.6,进行吸附-解吸附循环5次后,氯霉素印迹聚合物的性能稳定,可重复使用。将制备的氯霉素分子印迹聚合物作为富集材料,应用于鸡蛋样品中氯霉素的检测,回收率可达62.3%~81.1%,准确性好。
[Abstract]:Using chloramphenicol (chloramphenicol) as template, 2-vinylpyridine (2-Vp) as functional monomer, tetrahydrofuran and ionic liquid 1-#china_person0# -3-methylimidazolium tetrafluoroborate [BMIm] BF4 as reaction solvent, ethylene glycol dimethacrylate as crosslinking agent. The molecularly imprinted and non-imprinted polymers of chloramphenicol were synthesized by using azodiisobutyronitrile (AIBN) as initiator. The effects of functional monomers and solvents on the adsorption properties of imprinted polymers were optimized. The results showed that 2-vinylpyridine was used as functional monomer. The molecularly imprinted polymers synthesized by tetrahydrofuran and ionic liquid [BMIm] BF4 (volume ratio 1: 1) have high adsorption capacity for chloramphenicol. The imprinting factor of chloramphenicol molecularly imprinted polymer was 2.6. After 5 cycles of adsorption-desorption, the performance of chloramphenicol imprinted polymer was stable. The prepared chloramphenicol molecularly imprinted polymer was used as enrichment material and applied to the detection of chloramphenicol in egg samples. The recovery rate of chloramphenicol reached 62.3% 81.1% and the accuracy was good.
【作者单位】：江西省科学院应用化学研究所;华南师范大学化学与环境学院;
【基金】：江西省自然科学基金项目(201402BAB203017)
【分类号】：O631.3

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