XRF,PXRD和FTIR的广藿香主要组分测定与表征

发布时间：2018-05-01 02:03

本文选题：广藿香 + 一水草酸钙　；参考：《光谱学与光谱分析》2017年12期

【摘要】：中药的质量控制和评价在现代化医学发展中起着至关重要的作用。为了客观和高精度的鉴别中药材特性,实现对中药材质量稳定性的控制,利用XRF,PXRD和FTIR对广藿香的主要组分及微结构进行测定,建立了基于XRF,PXRD和FTIR鉴别中药材主要组分及产地特征的新方法。实验结果表明,广藿香中含有K,Ca,Cl,Si和P等多种元素,独有的元素特征谱是广藿香形成药效好的道地药材的部分物质基础。广藿香含有大量的晶态物质及少量非晶态物质,且Ca在其中以CaC_2O_4·H_2O状态存在,被检样品中该晶体物质含量的多少与相关锐峰的强弱成正比。对FTIR谱峰进行了归属与分析,提供了醇类、黄酮及草酸钙等物质的化学组分信息。该法联用XRF,PXRD和FTIR技术从元素、原子和分子微观层面客观地表征了广藿香主要组分及微结构的相关信息,避免了单独使用某种方法的片面性,能避免因复杂的前处理导致样品固有组分的改变,具有快速、简洁、再现性好及易于接受等优点,为广藿香及其他中药材的质量控制和品质评价提供一种新方法。
[Abstract]:The quality control and evaluation of traditional Chinese medicine play an important role in the development of modern medicine. In order to identify the characteristics of Chinese medicinal materials objectively and accurately and to control the quality and stability of Chinese medicinal materials, the main components and microstructure of patchouli were determined by XRF PXRD and FTIR. A new method for identification of main components and origin characteristics of Chinese medicinal materials based on XRF PXRD and FTIR was established. The results showed that patchouli contained many elements, such as K _ (+) CaCl _ (1) Si and P, and the unique elemental characteristic spectrum was part of the material basis for the formation of patchouli. Patchouli contains a large amount of crystalline substance and a small amount of amorphous substance, in which Ca exists in CaC_2O_4 H 2O state. The content of the substance in the sample is directly proportional to the intensity of the sharp peak. The FTIR peaks were assigned and analyzed, and the chemical components of alcohols, flavonoids and calcium oxalate were provided. The method combines XRF PXRD and FTIR techniques to characterize objectively the information about the main components and microstructure of patchouli patchouli at the element, atomic and molecular microcosmic levels, thus avoiding the one-sidedness of using a method alone. It can avoid the change of the inherent components of the sample due to complicated pretreatment. It has the advantages of rapidity, simplicity, reproducibility and acceptability. It provides a new method for the quality control and quality evaluation of patchouli and other Chinese medicinal materials.
【作者单位】：燕山大学河北省测试计量技术与仪器重点实验室;河北环境工程学院;
【基金】：国家自然科学基金项目(61471312) 河北省自然科学基金项目(F2015203240)资助
【分类号】：O657.3;R284.1

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