叶绿素类四吡咯大环分子的重排反应

发布时间：2018-06-03 14:08

本文选题：叶绿素 + 二氢卟吩　；参考：《化学进展》2017年Z2期

【摘要】：广泛存在于自然界的叶绿素是高等植物进行光合作用的重要物质,它们的非对称性碳架结构、芳香性大环色基和连带的各种取代基团形成了一类特殊的天然产物,其不同的降解产物在光动力治疗、染料敏化太阳能电池和人工光合成等诸多领域得以广泛应用。叶绿素类大环分子中不同类型的芳香性π-体系、多区域的活性反应位点以及复杂的互变结构形成其独有的化学性质,叶绿素中的吡咯子环和氮杂轮烯结构的密切关联以及环上官能基团与母环离域体系的有效共轭,导致叶绿素类二氢卟吩经常发生各种重排反应,从不同的层面上充分地体现出重排类型的广泛性和反应历程的新颖性。这些特殊的化学转换一直是设计和构建具有新颖碳架结构和实际应用前景的大环化合物的有效途径,也是深入探讨叶绿素的基础理论、化学合成以及应用研究的重要切入点。为此,本文基于该类天然产物的化学修饰和结构转换,综述了近期叶绿素类四吡咯大环分子的重排反应研究。
[Abstract]:Chlorophyll, which widely exists in nature, is an important material for photosynthesis in higher plants. Their asymmetric carbon frame structure, aromatic macrocyclic chromophore and associated substituents form a special kind of natural products. Different degradation products have been widely used in photodynamic therapy, dye sensitized solar cells and artificial photosynthesis. Different types of aromatic 蟺-system, multi-region active reaction sites and complex reciprocal structures in macrocyclic chlorophyll molecules form their unique chemical properties. The close relationship between pyrrole ring and azohelene structure in chlorophyll and the effective conjugation between the energy group of the ring and the mother ring lead to a variety of rearrangement reactions of chlorophyll chlorin. It fully reflects the universality of the rearrangement type and the novelty of the reaction process from different levels. These special chemical transformations have been an effective way to design and construct macrocyclic compounds with novel carbon frame structure and practical application prospects, and are also an important entry point for further research on the basic theory, chemical synthesis and application of chlorophyll. Therefore, based on the chemical modification and structural transformation of this kind of natural products, the recent studies on the rearrangement of chlorophyll tetrapyrrole macrocyclic molecules are reviewed.
【作者单位】：烟台大学文经学院食品与生物工程系;烟台大学化学化工学院;
【基金】：国家自然科学基金项目(No.51472212) 山东省自然科学基金青年项目(No.ZR2015BQ012) 山东省高校科技计划项目(No.J15LC51)资助~~
【分类号】：O626.13;O621.259.3

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