基于QuEChERS法提取液相色谱-串联质谱法测定新会陈皮中的9种真菌毒素和农药残留

发布时间：2018-06-19 13:58

本文选题：Qu + ECh　；参考：《分析测试学报》2017年06期

【摘要】：建立了Qu ECh ERS-改性多壁碳纳米管提取净化结合液相色谱-质谱联用同时检测新会陈皮中6种真菌毒素和3种农药残留的分析方法,并对影响提取、净化、检测效率的因素进行了优化。以乙腈-水(80∶20)提取样品,适量改性多壁碳纳米管净化后,净化液直接用HPLC-MS/MS进行测定,选择多反应监测模式,基质匹配标准溶液外标法定量。在优化实验条件下,9种目标化合物在各自线性范围内均具有良好的线性关系,相关系数为0.983 8~0.998 2,检出限(S/N=3)为0.18~10μg/kg。在低、中、高3个加标水平的平均回收率为72.4%~106%,相对标准偏差为2.2%~7.4%。该法准确、灵敏度高操作简单快速,可满足新会陈皮中上述9种化合物同时测定的要求,应用于真菌毒素和农药残留的快速筛查和确证,结果满意。
[Abstract]:A method for the simultaneous determination of 6 mycotoxins and 3 pesticide residues in Xinhui pericarp by extraction and purification of qu ECh ERS- modified multiwalled carbon nanotubes was established. The factors of detection efficiency were optimized. The samples were extracted from acetonitrile-water (80: 20). After purifying the modified multi-walled carbon nanotubes, the purified solution was directly determined by HPLC-MS / MS, the multi-reaction monitoring model was selected, and the matrix matching standard solution external standard method was used to quantify the sample. Under the optimized experimental conditions, all the nine target compounds have a good linear relationship in their respective linear range, the correlation coefficient is 0.983 ~ 0.998 ~ 2, and the detection limit is 0.1810 渭 g / kg 路kg ~ (-1) 路L ~ (-1) ~ (-1) ~ (-1) ~ (-1) ~ (-1) ~ (-1) ~ (-1) ~ (-1) ~ (-1). The average recoveries of the three standard addition levels were 72.4% and 106.The relative standard deviation was 2.2% and 7.4% respectively. The method is accurate and sensitive. Easy operation? It can meet the requirements of simultaneous determination of the above nine compounds in Xinhui pericarp. It has been applied to the rapid screening and confirmation of mycotoxins and pesticide residues with satisfactory results.
【作者单位】：新会出入境检验检疫局;阳江出入境检验检疫局;
【基金】：国家质检总局科技项目(2016IK066) 江门市科技项目(20161408)
【分类号】：O657.63;R284.1

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