DNA调控的银纳米簇的合成及应用进展

发布时间：2018-10-12 12:32

【摘要】：荧光银纳米簇具有独特的物理及化学性质,凭借合成简便、荧光强度大、量子产率高、抗光漂白能力强、荧光发射波长可调及生物相容性好等优势,近年来在生物检测、成像分析等领域受到了越来越广泛的关注.文章基于DNA调控荧光银纳米簇的合成方法研究,综述了关于DNA序列、长度、二级结构等对银纳米簇荧光性质的影响规律,并详细介绍荧光银纳米簇在分析检测和生物成像应用方面的最新进展.相信随着荧光纳米簇材料的应用优势逐步凸显,该领域的研究将吸引更广泛的关注,并推动相关交叉学科的进展.
[Abstract]:Due to its unique physical and chemical properties, fluorescent silver nanoclusters have many advantages such as simple synthesis, high fluorescence intensity, high quantum yield, strong photobleaching resistance, adjustable fluorescence emission wavelength and good biocompatibility. Imaging analysis and other fields have attracted more and more attention. Based on the synthesis of silver nanoclusters regulated by DNA, the effects of DNA sequence, length and secondary structure on the fluorescence properties of silver nanoclusters are reviewed. The latest development of fluorescent silver nanoclusters in analytical detection and bioimaging applications is also introduced in detail. It is believed that with the application advantages of fluorescent nanoclusters gradually prominent, the research in this field will attract more attention and promote the development of related interdisciplinary disciplines.
【作者单位】： 华南师范大学生物光子学研究院激光生命科学教育部重点实验室;
【基金】：国家自然科学基金项目(21475048) 广东省自然科学杰出青年科学基金(2014A030306008) 广东省特支计划(2014TQ01R559) 华南师范大学青年教师科研培育基金项目(671074)
【分类号】：O657.3

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