α-乙酰基二硫缩烯酮Vilsmeier反应在共轭三烯化合物合成中的应用
发布时间：2018-10-25 13:55
【摘要】：以α-乙酰基二硫缩烯酮为起始原料,通过与Vilsmeier试剂反应得到亚胺盐正离子中间体,利用亚胺盐正离子中间体与碳亲核体反应,成功制备了多取代共轭三烯类化合物.该方法具有原料易得、反应条件温和及实验步骤简单等优点.该反应不仅建立了一种简单、有效合成多取代共轭三烯化合物新方法,而且扩展了α-乙酰基二硫缩烯酮类化合物在有机合成中的进一步应用.
[Abstract]:Using 伪 -acetyldithioketene as the starting material, the imine ion intermediate was prepared by reaction with Vilsmeier reagent. The polysubstituted conjugated trienes were prepared by the reaction of imine ion intermediate with carbon nucleophile. The method has the advantages of easy availability of raw materials, mild reaction conditions and simple experimental steps. This reaction not only established a simple and effective method for the synthesis of polysubstituted conjugated trienes, but also extended the further application of 伪 -acetyldithioenones in organic synthesis.
【作者单位】： 吉林工商学院食品工程学院;东北师范大学化学学院;
【基金】：国家自然科学基金资助项目(21172032)
【分类号】：O621.25
本文编号：2293891
[Abstract]:Using 伪 -acetyldithioketene as the starting material, the imine ion intermediate was prepared by reaction with Vilsmeier reagent. The polysubstituted conjugated trienes were prepared by the reaction of imine ion intermediate with carbon nucleophile. The method has the advantages of easy availability of raw materials, mild reaction conditions and simple experimental steps. This reaction not only established a simple and effective method for the synthesis of polysubstituted conjugated trienes, but also extended the further application of 伪 -acetyldithioenones in organic synthesis.
【作者单位】： 吉林工商学院食品工程学院;东北师范大学化学学院;
【基金】：国家自然科学基金资助项目(21172032)
【分类号】：O621.25
【相似文献】
相关期刊论文 前2条
1 钱定权,曹如珍,刘纶祖;Vilsmeier试剂近年来在有机合成中的应用[J];有机化学;2000年01期
2 ;[J];;年期
相关博士学位论文 前1条
1 信欣;Vilsmeier盐及其离子液体的合成、性质和应用研究[D];吉林大学;2009年
相关硕士学位论文 前1条
1 张岩峰;α-乙酰基二硫缩烯酮的Vilsmeier反应及其在有机合成中的应用[D];东北师范大学;2006年
，本文编号：2293891
本文链接：https://www.wllwen.com/kejilunwen/huaxue/2293891.html
教材专著
