以氧化石墨烯为酸催化剂制备2,5-二甲基-N-苯基吡咯（英文）
发布时间：2019-04-27 21:48
【摘要】：介绍了氧化石墨烯作为一种高效且可回收的催化剂应用于2,5-己二酮与苯胺通过Paal-Knorr缩合反应合成N-取代吡咯。研究了反应时间、反应温度、溶剂、催化剂用量以及苯胺与2,5-己二酮的摩尔比对2,5-二甲基-N-苯基吡咯收率的影响。通过原位核磁技术在分子水平上跟踪了Paal-Knorr缩合的反应过程。结果表明在25℃下通过氧化石墨烯的催化作用反应6 h后吡咯的最大收率可达到90%。氧化石墨烯易回收,且经5次回收使用后还能表现出很好的循环使用性和高催化性能。
[Abstract]:N-substituted pyrrole was synthesized by Paal-Knorr condensation of 2,5-hexanedione with aniline using graphene oxide as an efficient and recyclable catalyst. The effects of reaction time, reaction temperature, solvent, catalyst amount and molar ratio of aniline to 2,5-hexanedione on the yield of 2,5-dimethyl-N-phenyl pyrrole were studied. In situ NMR technique was used to track the reaction process of Paal-Knorr condensation at the molecular level. The results show that the maximum yield of pyrrole can reach 90% after 6 h of catalytic reaction of graphene oxide at 25 鈩，
本文编号：2467334
[Abstract]:N-substituted pyrrole was synthesized by Paal-Knorr condensation of 2,5-hexanedione with aniline using graphene oxide as an efficient and recyclable catalyst. The effects of reaction time, reaction temperature, solvent, catalyst amount and molar ratio of aniline to 2,5-hexanedione on the yield of 2,5-dimethyl-N-phenyl pyrrole were studied. In situ NMR technique was used to track the reaction process of Paal-Knorr condensation at the molecular level. The results show that the maximum yield of pyrrole can reach 90% after 6 h of catalytic reaction of graphene oxide at 25 鈩，
本文编号：2467334
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