间歇模拟移动床的优化控制

发布时间：2019-05-23 21:05

【摘要】：随着模拟移动床色谱分离技术的发展,其在石油化工、制糖工业以及药材制作等方面得到了广泛的应用。近年来为了进一步提高模拟移动床的分离效果,国外研究者提出了间歇模拟移动床。由于间歇模拟移动床的设计结构简单、成本低,并且比常规的模拟移动床具有更高的分离性能和生产率,因此对间歇模拟移动床的色谱分离过程的优化不仅有着重要的理论价值,还对实际应用起到重要的作用。对间歇模拟移动床分离过程的优化问题已经成为重点研究对象。本文采用改进移动渐近线算法对间歇模拟移动床进行操作过程优化,通过在线优化控制的方法对间歇模拟移动床的提取液纯度、提余液纯度、生产率和溶剂消耗等方面进行仿真分析,并通过三角理论证明其可行性,同时将改进移动渐近线算法的优化结果与NSGA-Ⅱ算法的优化结果进行比较。最后将改进移动渐近线算法分别应用到模拟移动床与间歇模拟移动床进行仿真研究,并对结果进行对比分析。本文工作包括:(1)详述了模拟移动床的发展历程,国内外研究现状和间歇模拟移动床色谱分离的基本原理以及常用的色谱模型。(2)在平衡扩散模型的基础上,采用隐式差分法对其进行求解,并应用MATLAB软件进行仿真研究。(3)为了提高间歇模拟移动床的分离性能,本文采用了改进移动渐近线算法,通过在线优化控制策略来研究最大化提取液纯度和提余液纯度、最大化生产率和最小化溶剂消耗等问题。并用三角理论进行可行性分析,然后将改进移动渐近线算法与NSGA-Ⅱ算法的仿真结果进行比较讨论。最后将改进移动渐近线算法分别应用到模拟移动床与间歇模拟移动床进行仿真研究,并对结果进行对比分析。
[Abstract]:With the development of simulated moving bed chromatography, it has been widely used in petrochemical industry, sugar industry and medicinal material production. In recent years, in order to further improve the separation effect of simulated moving bed, foreign researchers have proposed intermittent simulated moving bed. Because the design structure of intermittent simulated moving bed is simple, the cost is low, and it has higher separation performance and productivity than the conventional simulated moving bed. Therefore, the optimization of chromatographic separation process of intermittent simulated moving bed not only has important theoretical value, but also plays an important role in practical application. The optimization of intermittent simulated moving bed separation process has become the focus of research. In this paper, the improved moving asymptote algorithm is used to optimize the operation process of the intermittent simulated moving bed, and the purity of the extract and the residual liquid of the intermittent simulated moving bed are optimized by the method of on-line optimization control. The productivity and solvent consumption are simulated and analyzed, and its feasibility is proved by trigonometric theory. At the same time, the optimization results of the improved moving asymptote algorithm are compared with those of NSGA- II algorithm. Finally, the improved moving asymptote algorithm is applied to the simulation of simulated moving bed and intermittent simulated moving bed respectively, and the results are compared and analyzed. The work of this paper includes: (1) the development of simulated moving bed, the research status at home and abroad, the basic principle of intermittent simulated moving bed chromatography separation and the commonly used chromatographic models are described in detail. (2) on the basis of equilibrium diffusion model, The implicit difference method is used to solve it, and the simulation is carried out by MATLAB software. (3) in order to improve the separation performance of intermittent simulated moving bed, an improved moving asymptote algorithm is adopted in this paper. Through the on-line optimization control strategy, the problems of maximizing the purity of extract and residual liquid, maximizing productivity and minimizing solvent consumption are studied. The feasibility of the improved moving asymptote algorithm is analyzed by trigonometric theory, and the simulation results of the improved moving asymptote algorithm and NSGA- II algorithm are compared and discussed. Finally, the improved moving asymptote algorithm is applied to the simulation of simulated moving bed and intermittent simulated moving bed respectively, and the results are compared and analyzed.
【学位授予单位】：辽宁科技大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：O652.6

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